Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth?
Obesity is one of the major epidemics of this millennium, and its incidence is growing worldwide. Following the epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) has become a disease of increasing prevalence and a leading cause of morbidity and mortality closely related to cardiovascula...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-01-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3921/7/1/12 |
| _version_ | 1797701251416195072 |
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| author | Hamza El Hadi Roberto Vettor Marco Rossato |
| author_facet | Hamza El Hadi Roberto Vettor Marco Rossato |
| author_sort | Hamza El Hadi |
| collection | DOAJ |
| description | Obesity is one of the major epidemics of this millennium, and its incidence is growing worldwide. Following the epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) has become a disease of increasing prevalence and a leading cause of morbidity and mortality closely related to cardiovascular disease, malignancies, and cirrhosis. It is believed that oxidative stress is a main player in the development and progression of NAFLD. Currently, a pharmacological approach has become necessary in NAFLD because of a failure to modify lifestyle and dietary habits in most patients. Vitamin E is a potent antioxidant that has been shown to reduce oxidative stress in NAFLD. This review summarizes the biological activities of vitamin E, with a primary focus on its therapeutic efficacy in NAFLD. |
| first_indexed | 2024-03-12T04:32:46Z |
| format | Article |
| id | doaj.art-503493ef1af14942bdd58a2f22ed0b57 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-12T04:32:46Z |
| publishDate | 2018-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-503493ef1af14942bdd58a2f22ed0b572023-09-03T09:59:14ZengMDPI AGAntioxidants2076-39212018-01-01711210.3390/antiox7010012antiox7010012Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth?Hamza El Hadi0Roberto Vettor1Marco Rossato2Internal Medicine 3, Department of Medicine—DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyInternal Medicine 3, Department of Medicine—DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyInternal Medicine 3, Department of Medicine—DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyObesity is one of the major epidemics of this millennium, and its incidence is growing worldwide. Following the epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) has become a disease of increasing prevalence and a leading cause of morbidity and mortality closely related to cardiovascular disease, malignancies, and cirrhosis. It is believed that oxidative stress is a main player in the development and progression of NAFLD. Currently, a pharmacological approach has become necessary in NAFLD because of a failure to modify lifestyle and dietary habits in most patients. Vitamin E is a potent antioxidant that has been shown to reduce oxidative stress in NAFLD. This review summarizes the biological activities of vitamin E, with a primary focus on its therapeutic efficacy in NAFLD.http://www.mdpi.com/2076-3921/7/1/12vitamin Enonalcoholic fatty liver diseaseobesityoxidative stress |
| spellingShingle | Hamza El Hadi Roberto Vettor Marco Rossato Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? Antioxidants vitamin E nonalcoholic fatty liver disease obesity oxidative stress |
| title | Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? |
| title_full | Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? |
| title_fullStr | Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? |
| title_full_unstemmed | Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? |
| title_short | Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? |
| title_sort | vitamin e as a treatment for nonalcoholic fatty liver disease reality or myth |
| topic | vitamin E nonalcoholic fatty liver disease obesity oxidative stress |
| url | http://www.mdpi.com/2076-3921/7/1/12 |
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