Skeletal muscle mTORC1 regulates neuromuscular junction stability

Skeletal muscle mTORC1 regulates neuromuscular junction stability

Abstract Background Skeletal muscle is a plastic tissue that can adapt to different stimuli. It is well established that Mammalian Target of Rapamycin Complex 1 (mTORC1) signalling is a key modulator in mediating increases in skeletal muscle mass and function. However, the role of mTORC1 signalling...

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Bibliographic Details
Main Authors: Martina Baraldo, Alessia Geremia, Marco Pirazzini, Leonardo Nogara, Francesca Solagna, Clara Türk, Hendrik Nolte, Vanina Romanello, Aram Megighian, Simona Boncompagni, Marcus Kruger, Marco Sandri, Bert Blaauw
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
mTOR
NMJ
Autophagy
Mitochondrial dysfunction
Online Access:https://doi.org/10.1002/jcsm.12496

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