Monte Carlo Characterization of the Trimage Brain PET System

The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three squa...

Full description

Bibliographic Details
Main Authors: Luigi Masturzo, Pietro Carra, Paola Anna Erba, Matteo Morrocchi, Alessandro Pilleri, Giancarlo Sportelli, Nicola Belcari
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Imaging
Subjects:
Online Access:https://www.mdpi.com/2313-433X/8/2/21
_version_ 1797479030261284864
author Luigi Masturzo
Pietro Carra
Paola Anna Erba
Matteo Morrocchi
Alessandro Pilleri
Giancarlo Sportelli
Nicola Belcari
author_facet Luigi Masturzo
Pietro Carra
Paola Anna Erba
Matteo Morrocchi
Alessandro Pilleri
Giancarlo Sportelli
Nicola Belcari
author_sort Luigi Masturzo
collection DOAJ
description The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three square detector modules based on dual sstaggered LYSO:Ce matrices read out by SiPMs. Using Monte Carlo simulations and following NEMA (National Electrical Manufacturers Association) guidelines, image quality procedures have been applied to evaluate the performance of the PET component of the system. The performance are reported in terms of spatial resolution, uniformity, recovery coefficient, spill over ratio, noise equivalent count rate (NECR) and scatter fraction. The results show that the TRIMAGE system is at the top of the current brain PET technologies.
first_indexed 2024-03-09T21:40:03Z
format Article
id doaj.art-50372eb4f22a49758dd0dcbefe40a586
institution Directory Open Access Journal
issn 2313-433X
language English
last_indexed 2024-03-09T21:40:03Z
publishDate 2022-01-01
publisher MDPI AG
record_format Article
series Journal of Imaging
spelling doaj.art-50372eb4f22a49758dd0dcbefe40a5862023-11-23T20:33:04ZengMDPI AGJournal of Imaging2313-433X2022-01-01822110.3390/jimaging8020021Monte Carlo Characterization of the Trimage Brain PET SystemLuigi Masturzo0Pietro Carra1Paola Anna Erba2Matteo Morrocchi3Alessandro Pilleri4Giancarlo Sportelli5Nicola Belcari6Department of Physics “E. Fermi”, University of Pisa, 56127 Pisa, ItalyDepartment of Physics “E. Fermi”, University of Pisa, 56127 Pisa, ItalyDepartment of Translational Research and New Technology in Medicine and Surgery, Regional Center of Nuclear Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, 56126 Pisa, ItalyDepartment of Physics “E. Fermi”, University of Pisa, 56127 Pisa, ItalyDepartment of Physics “E. Fermi”, University of Pisa, 56127 Pisa, ItalyDepartment of Physics “E. Fermi”, University of Pisa, 56127 Pisa, ItalyDepartment of Physics “E. Fermi”, University of Pisa, 56127 Pisa, ItalyThe TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three square detector modules based on dual sstaggered LYSO:Ce matrices read out by SiPMs. Using Monte Carlo simulations and following NEMA (National Electrical Manufacturers Association) guidelines, image quality procedures have been applied to evaluate the performance of the PET component of the system. The performance are reported in terms of spatial resolution, uniformity, recovery coefficient, spill over ratio, noise equivalent count rate (NECR) and scatter fraction. The results show that the TRIMAGE system is at the top of the current brain PET technologies.https://www.mdpi.com/2313-433X/8/2/21brain PETMonte Carlo characterizationPET/MRTRIMAGE projectNEMA
spellingShingle Luigi Masturzo
Pietro Carra
Paola Anna Erba
Matteo Morrocchi
Alessandro Pilleri
Giancarlo Sportelli
Nicola Belcari
Monte Carlo Characterization of the Trimage Brain PET System
Journal of Imaging
brain PET
Monte Carlo characterization
PET/MR
TRIMAGE project
NEMA
title Monte Carlo Characterization of the Trimage Brain PET System
title_full Monte Carlo Characterization of the Trimage Brain PET System
title_fullStr Monte Carlo Characterization of the Trimage Brain PET System
title_full_unstemmed Monte Carlo Characterization of the Trimage Brain PET System
title_short Monte Carlo Characterization of the Trimage Brain PET System
title_sort monte carlo characterization of the trimage brain pet system
topic brain PET
Monte Carlo characterization
PET/MR
TRIMAGE project
NEMA
url https://www.mdpi.com/2313-433X/8/2/21
work_keys_str_mv AT luigimasturzo montecarlocharacterizationofthetrimagebrainpetsystem
AT pietrocarra montecarlocharacterizationofthetrimagebrainpetsystem
AT paolaannaerba montecarlocharacterizationofthetrimagebrainpetsystem
AT matteomorrocchi montecarlocharacterizationofthetrimagebrainpetsystem
AT alessandropilleri montecarlocharacterizationofthetrimagebrainpetsystem
AT giancarlosportelli montecarlocharacterizationofthetrimagebrainpetsystem
AT nicolabelcari montecarlocharacterizationofthetrimagebrainpetsystem