Mitochondrial Ca2+ Overload Leads to Mitochondrial Oxidative Stress and Delayed Meiotic Resumption in Mouse Oocytes

Mitochondrial Ca2+ Overload Leads to Mitochondrial Oxidative Stress and Delayed Meiotic Resumption in Mouse Oocytes

Overweight or obese women seeking pregnancy is becoming increasingly common. Human maternal obesity gives rise to detrimental effects during reproduction. Emerging evidence has shown that these abnormities are likely attributed to oocyte quality. Oxidative stress induces poor oocyte conditions, but...

Full description

Bibliographic Details
Main Authors: Luyao Zhang, Zichuan Wang, Tengfei Lu, Lin Meng, Yan Luo, Xiangwei Fu, Yunpeng Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mitochondria
calcium overload
oocytes
meiosis
obesity
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.580876/full

Similar Items

Similar Items