Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients
<i>Fusarium musae</i> has recently been described as a cross-kingdom pathogen causing post-harvest disease in bananas and systemic and superficial infection in humans. The taxonomic identity of fungal cross-kingdom pathogens is essential for confirming the identification of the species o...
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| Format: | Article |
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MDPI AG
2022-05-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/10/6/1115 |
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| author | Luca Degradi Valeria Tava Anna Prigitano Maria Carmela Esposto Anna Maria Tortorano Marco Saracchi Andrea Kunova Paolo Cortesi Matias Pasquali |
| author_facet | Luca Degradi Valeria Tava Anna Prigitano Maria Carmela Esposto Anna Maria Tortorano Marco Saracchi Andrea Kunova Paolo Cortesi Matias Pasquali |
| author_sort | Luca Degradi |
| collection | DOAJ |
| description | <i>Fusarium musae</i> has recently been described as a cross-kingdom pathogen causing post-harvest disease in bananas and systemic and superficial infection in humans. The taxonomic identity of fungal cross-kingdom pathogens is essential for confirming the identification of the species on distant infected hosts. Understanding the level of variability within the species is essential to decipher the population homogeneity infecting human and plant hosts. In order to verify that <i>F. musae</i> strains isolated from fruits and patients are part of a common population and to estimate their overall diversity, we assembled, annotated and explored the diversity of the mitogenomes of 18 <i>F. musae</i> strains obtained from banana fruits and human patients. The mitogenomes showed a high level of similarity among strains with different hosts’ origins, with sizes ranging from 56,493 to 59,256 bp. All contained 27 tRNA genes and 14 protein-coding genes, rps3 protein, and small and large ribosomal subunits (rns and rnl). Variations in the number of endonucleases were detected. A comparison of mitochondrial endonucleases distribution with a diverse set of <i>Fusarium</i> mitogenomes allowed us to specifically discriminate <i>F. musae</i> from its sister species <i>F. verticillioides</i> and the other <i>Fusarium</i> species. Despite the diversity in <i>F. musae</i> mitochondria, strains from bananas and strains from human patients group together, indirectly confirming <i>F. musae</i> as a cross-kingdom pathogen. |
| first_indexed | 2024-03-09T22:59:56Z |
| format | Article |
| id | doaj.art-5037fe34bdfb4c119b76fdb3b8868006 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T22:59:56Z |
| publishDate | 2022-05-01 |
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| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-5037fe34bdfb4c119b76fdb3b88680062023-11-23T18:03:14ZengMDPI AGMicroorganisms2076-26072022-05-01106111510.3390/microorganisms10061115Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human PatientsLuca Degradi0Valeria Tava1Anna Prigitano2Maria Carmela Esposto3Anna Maria Tortorano4Marco Saracchi5Andrea Kunova6Paolo Cortesi7Matias Pasquali8Department of Food, Environmental and Nutritional Science (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, ItalyDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, ItalyDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133 Milan, ItalyDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133 Milan, ItalyDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133 Milan, ItalyDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, ItalyDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, ItalyDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, ItalyDepartment of Food, Environmental and Nutritional Science (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy<i>Fusarium musae</i> has recently been described as a cross-kingdom pathogen causing post-harvest disease in bananas and systemic and superficial infection in humans. The taxonomic identity of fungal cross-kingdom pathogens is essential for confirming the identification of the species on distant infected hosts. Understanding the level of variability within the species is essential to decipher the population homogeneity infecting human and plant hosts. In order to verify that <i>F. musae</i> strains isolated from fruits and patients are part of a common population and to estimate their overall diversity, we assembled, annotated and explored the diversity of the mitogenomes of 18 <i>F. musae</i> strains obtained from banana fruits and human patients. The mitogenomes showed a high level of similarity among strains with different hosts’ origins, with sizes ranging from 56,493 to 59,256 bp. All contained 27 tRNA genes and 14 protein-coding genes, rps3 protein, and small and large ribosomal subunits (rns and rnl). Variations in the number of endonucleases were detected. A comparison of mitochondrial endonucleases distribution with a diverse set of <i>Fusarium</i> mitogenomes allowed us to specifically discriminate <i>F. musae</i> from its sister species <i>F. verticillioides</i> and the other <i>Fusarium</i> species. Despite the diversity in <i>F. musae</i> mitochondria, strains from bananas and strains from human patients group together, indirectly confirming <i>F. musae</i> as a cross-kingdom pathogen.https://www.mdpi.com/2076-2607/10/6/1115cross-kingdom pathogen<i>F. fujikuroi</i> species complexmitochondrial diversity |
| spellingShingle | Luca Degradi Valeria Tava Anna Prigitano Maria Carmela Esposto Anna Maria Tortorano Marco Saracchi Andrea Kunova Paolo Cortesi Matias Pasquali Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients Microorganisms cross-kingdom pathogen <i>F. fujikuroi</i> species complex mitochondrial diversity |
| title | Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients |
| title_full | Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients |
| title_fullStr | Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients |
| title_full_unstemmed | Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients |
| title_short | Exploring Mitogenomes Diversity of <i>Fusarium musae</i> from Banana Fruits and Human Patients |
| title_sort | exploring mitogenomes diversity of i fusarium musae i from banana fruits and human patients |
| topic | cross-kingdom pathogen <i>F. fujikuroi</i> species complex mitochondrial diversity |
| url | https://www.mdpi.com/2076-2607/10/6/1115 |
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