4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes

4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes

OBJECTIVES/GOALS: Lupus lesional skin has elevated interferon expression, is highly colonized with Staphylococcus aureus (50%) and has no FDA-approved treatment options. We decided to investigate the effect of topical antibiotics on lupus lesional skin to determine whether it affects inflammatory ge...

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Bibliographic Details
Main Authors: Sirisha Sirobhushanam, Allison C Billi, Celine C Berthier, Lam C Tsoi, Johann E Gudjonsson, J Michelle Kahlenberg
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120003908/type/journal_article

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