Poly(ethylene glycol)-Lipid-Conjugated Antibodies Enhance Dendritic Cell Phagocytosis of Apoptotic Cancer Cells

Poly(ethylene glycol)-Lipid-Conjugated Antibodies Enhance Dendritic Cell Phagocytosis of Apoptotic Cancer Cells

A simple method for attaching immunoglobulin G (IgG) on the cell surface was successfully developed for enhancing phagocytosis of apoptotic tumor cells (ATCs) by dendritic cells (DCs) <em>ex vivo</em>. By conjugating with a poly(ethylene glycol) (PEG)-lipid, named the bio...

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Bibliographic Details
Main Authors:	Teruyuki Nagamune, Satoshi Takamori, Satoshi Yamaguchi, Yoichiro Sugimoto, Urara Tomita
Format:	Article
Language:	English
Published:	MDPI AG 2012-04-01
Series:	Pharmaceuticals
Subjects:	antibody conjugates dendritic cell vaccine antibody-dependent cell phagocytosis poly(ethylene glycol)-lipid
Online Access:	http://www.mdpi.com/1424-8247/5/5/405

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