Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features
BackgroundHepatoid adenocarcinoma of the stomach (HAS) is a rare subtype of gastric cancer with poor prognosis, and its clinicopathological features are not well understood, so the pathology from the clinical biopsy is easily misdiagnosed, especially for special or atypical HAS. We present an extrem...
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| Format: | Article |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1016447/full |
| _version_ | 1797955962999406592 |
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| author | Xinglong Wu Lianjun Di Chengfang Li Suyuan Zhang Na Tan Jiajia Huang Biguang Tuo |
| author_facet | Xinglong Wu Lianjun Di Chengfang Li Suyuan Zhang Na Tan Jiajia Huang Biguang Tuo |
| author_sort | Xinglong Wu |
| collection | DOAJ |
| description | BackgroundHepatoid adenocarcinoma of the stomach (HAS) is a rare subtype of gastric cancer with poor prognosis, and its clinicopathological features are not well understood, so the pathology from the clinical biopsy is easily misdiagnosed, especially for special or atypical HAS. We present an extremely rare early HAS with signet ring cell carcinoma and evaluate its clinicopathological features.Case presentationA 51-year-old female patient of Chinese Han ethnicity with upper abdominal pain for 5 years and worsened abdominal pain for 1 month was admitted to our hospital. Esophagogastroduodenoscopy showed a submucosal tumor-like elevated lesion with central depression in the greater curvature of the junction between the antrum and body. Histopathological examination from the biopsy revealed medium–low-differentiation adenocarcinoma with signet ring cell carcinoma. Radical gastrectomy was performed, and the final diagnosis was early HAS with signet ring cell carcinoma.ConclusionsHAS with signet ring cell carcinoma is a special type of HAS and extremely rare. It is first presented for this extremely rare type of HAS, which contributes to strengthen the understanding for the clinicopathological characteristics of HAS and especially promote early detection of HAS. |
| first_indexed | 2024-04-10T23:42:31Z |
| format | Article |
| id | doaj.art-5044d970be0844699022a47a69013dcf |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-10T23:42:31Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-5044d970be0844699022a47a69013dcf2023-01-11T06:36:05ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-01-011210.3389/fonc.2022.10164471016447Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological featuresXinglong Wu0Lianjun Di1Chengfang Li2Suyuan Zhang3Na Tan4Jiajia Huang5Biguang Tuo6Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, ChinaBackgroundHepatoid adenocarcinoma of the stomach (HAS) is a rare subtype of gastric cancer with poor prognosis, and its clinicopathological features are not well understood, so the pathology from the clinical biopsy is easily misdiagnosed, especially for special or atypical HAS. We present an extremely rare early HAS with signet ring cell carcinoma and evaluate its clinicopathological features.Case presentationA 51-year-old female patient of Chinese Han ethnicity with upper abdominal pain for 5 years and worsened abdominal pain for 1 month was admitted to our hospital. Esophagogastroduodenoscopy showed a submucosal tumor-like elevated lesion with central depression in the greater curvature of the junction between the antrum and body. Histopathological examination from the biopsy revealed medium–low-differentiation adenocarcinoma with signet ring cell carcinoma. Radical gastrectomy was performed, and the final diagnosis was early HAS with signet ring cell carcinoma.ConclusionsHAS with signet ring cell carcinoma is a special type of HAS and extremely rare. It is first presented for this extremely rare type of HAS, which contributes to strengthen the understanding for the clinicopathological characteristics of HAS and especially promote early detection of HAS.https://www.frontiersin.org/articles/10.3389/fonc.2022.1016447/fullcase reportclinicopathological featurehepatoid adenocarcinomasignet ring cell carcinomastomach |
| spellingShingle | Xinglong Wu Lianjun Di Chengfang Li Suyuan Zhang Na Tan Jiajia Huang Biguang Tuo Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features Frontiers in Oncology case report clinicopathological feature hepatoid adenocarcinoma signet ring cell carcinoma stomach |
| title | Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features |
| title_full | Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features |
| title_fullStr | Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features |
| title_full_unstemmed | Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features |
| title_short | Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features |
| title_sort | early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma a case report and clinicopathological features |
| topic | case report clinicopathological feature hepatoid adenocarcinoma signet ring cell carcinoma stomach |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.1016447/full |
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