Developmental exposure to chlordecone induces transgenerational effects in somatic prostate tissue which are associated with epigenetic histone trimethylation changes

Developmental exposure to chlordecone induces transgenerational effects in somatic prostate tissue which are associated with epigenetic histone trimethylation changes

Background: Chlordecone (CD), also known as Kepone, is an organochlorine insecticide that has been used in banana crops in the French West Indies. Due to long-term contamination of soils and water, the population is still exposed to CD. Exposure to CD in adulthood is associated with an increased ris...

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Bibliographic Details
Main Authors: Louis Legoff, Shereen Cynthia D'Cruz, Morgane Lebosq, Aurore Gely-Pernot, Katia Bouchekhchoukha, Christine Monfort, Pierre-Yves Kernanec, Sergei Tevosian, Luc Multigner, Fatima Smagulova
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Environment International
Subjects:
Chlordecone
Prostate
PIN
Transgenerational inheritance
Epigenetics
DOHaD
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412021000970

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