Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice.
There is no proven medical approach to attenuating expansion and rupture of abdominal aortic aneurysms (AAAs). One approach that is currently being investigated is the use of doxycycline. Despite being primarily used as an antimicrobial drug, doxycycline has been proposed to function in reducing AAA...
Main Authors: | Xiaojie Xie, Hong Lu, Jessica J Moorleghen, Deborah A Howatt, Debra L Rateri, Lisa A Cassis, Alan Daugherty |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3459927?pdf=render |
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