Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene

Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene

Abstract INTRODUCTION Mutations in the propeller domain of the Plasmodium falciparum kelch13 (k13) gene are associated with artemisinin resistance. METHODS: We developed a PCR protocol to sequence the pfk13 gene and determined its sequence in a batch of 50 samples collected from 2003 to 2016 in...

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Bibliographic Details
Main Authors: Francesca Chapadense, Ricardo Luiz Dantas Machado, Ana Maria Revorêdo da Silva Ventura, André Áreas, Renato Beilner Machado, Giselle Rachid Viana, Mariano Gustavo Zalis, Ana Maria de Castro, Pedro Cravo
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2019-02-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Malaria
Plasmodium falciparum
Artemisinin Resistance
Kelch 13
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100614&lng=en&tlng=en

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