Thiazide-associated hyponatremia attenuates the fracture-protective effect of thiazide: A population-based study.
<h4>Background</h4>Thiazide, a first-line therapy for hypertension, lowers blood pressure, increases bone mineral density, and reduces the risk of fractures. However, hyponatremia, an adverse effect of thiazide, is associated with increased risk of osteoporosis and fractures. It is curre...
Main Authors: | Lii-Jia Yang, Ping-Hsun Wu, Teng-Hui Huang, Ming-Yen Lin, Jer-Chia Tsai |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0208712 |
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