Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe
Background and purpose: The aim of this study was to review the published studies on the utilisation of radiotherapy in lung cancer (both small and non-small cell lung cancer, SCLC and NSCLC) patients in European countries with a population-based perspective. Material and methods: A literature searc...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
|
| Series: | Clinical and Translational Radiation Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405630823001428 |
| _version_ | 1797272411580661760 |
|---|---|
| author | Julieta Corral Josep M. Borras Yolande Lievens |
| author_facet | Julieta Corral Josep M. Borras Yolande Lievens |
| author_sort | Julieta Corral |
| collection | DOAJ |
| description | Background and purpose: The aim of this study was to review the published studies on the utilisation of radiotherapy in lung cancer (both small and non-small cell lung cancer, SCLC and NSCLC) patients in European countries with a population-based perspective. Material and methods: A literature search since January 2000 until December 2022 was carried out. Only English-published papers were included, and only European data was considered. PRISMA guidelines were followed. A scoping narrative review was undertaken due to the hetereogeneity of the published papers. Results: 38 papers were included in the analysis, with the majority from the Netherlands (52.6%) and the UK (18.4%). Large variability is observed in the reported radiotherapy utilisation, around 40% for NSCLC in general and between 26 and 42% in stage I NSCLC. Stereotactic body radiotherapy (SBRT) shows a wide range of utilisation across countries and over time, from 8 to 63%. Similary, in stage III lung cancer, chemoradiotherapy (CRT) utilisation varied considerably (11–70%). Eleven studies compared radiotherapy utilisation between older and younger age-groups, showing that younger patients receive more CRT, while the opposite applies for SBRT. An widespreadlack of data on relevant covariates such as comorbidty and health-services related variables is observed. Conclusion: The actual utilisation of radiotherapy for lung cancer reported in patterns-of-care studies (POCs) is notably lower than the evidence-based optimal utilisation. Important variability is observed by country, time period, stage at diagnosis and age. A wider use of POCs should be promoted to improve our knowledge on the actual application of evidence-based treatment recommendations. |
| first_indexed | 2024-03-07T14:28:57Z |
| format | Article |
| id | doaj.art-504f0977791e4390a3a62d04188be6b1 |
| institution | Directory Open Access Journal |
| issn | 2405-6308 |
| language | English |
| last_indexed | 2024-03-07T14:28:57Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical and Translational Radiation Oncology |
| spelling | doaj.art-504f0977791e4390a3a62d04188be6b12024-03-06T05:27:42ZengElsevierClinical and Translational Radiation Oncology2405-63082024-03-0145100717Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in EuropeJulieta Corral0Josep M. Borras1Yolande Lievens2Catalonian Cancer Plan, Department of Health, Barcelona, Spain; Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet, Barcelona, Spain; Corresponding author at: Catalonian Cancer Plan - Hospital Duran i Reynals, Gran Via de l’Hospitalet, 199, 08908-Hospitalet del Llobregat, Barcelona, Spain.Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet, Barcelona, Spain; Department of Clinical Sciences, University of Barcelona, SpainDepartment of Radiation Oncology, Ghent University Hospital, Ghent, Belgium; Faculty of Medicine and Health Sciences, Ghent University, Ghent, BelgiumBackground and purpose: The aim of this study was to review the published studies on the utilisation of radiotherapy in lung cancer (both small and non-small cell lung cancer, SCLC and NSCLC) patients in European countries with a population-based perspective. Material and methods: A literature search since January 2000 until December 2022 was carried out. Only English-published papers were included, and only European data was considered. PRISMA guidelines were followed. A scoping narrative review was undertaken due to the hetereogeneity of the published papers. Results: 38 papers were included in the analysis, with the majority from the Netherlands (52.6%) and the UK (18.4%). Large variability is observed in the reported radiotherapy utilisation, around 40% for NSCLC in general and between 26 and 42% in stage I NSCLC. Stereotactic body radiotherapy (SBRT) shows a wide range of utilisation across countries and over time, from 8 to 63%. Similary, in stage III lung cancer, chemoradiotherapy (CRT) utilisation varied considerably (11–70%). Eleven studies compared radiotherapy utilisation between older and younger age-groups, showing that younger patients receive more CRT, while the opposite applies for SBRT. An widespreadlack of data on relevant covariates such as comorbidty and health-services related variables is observed. Conclusion: The actual utilisation of radiotherapy for lung cancer reported in patterns-of-care studies (POCs) is notably lower than the evidence-based optimal utilisation. Important variability is observed by country, time period, stage at diagnosis and age. A wider use of POCs should be promoted to improve our knowledge on the actual application of evidence-based treatment recommendations.http://www.sciencedirect.com/science/article/pii/S2405630823001428Radiation OncologyLung CancerPatterns of careUtilisation |
| spellingShingle | Julieta Corral Josep M. Borras Yolande Lievens Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe Clinical and Translational Radiation Oncology Radiation Oncology Lung Cancer Patterns of care Utilisation |
| title | Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe |
| title_full | Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe |
| title_fullStr | Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe |
| title_full_unstemmed | Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe |
| title_short | Utilisation of radiotherapy in lung cancer: A scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe |
| title_sort | utilisation of radiotherapy in lung cancer a scoping narrative literature review with a focus on the introduction of evidence based therapeutic approaches in europe |
| topic | Radiation Oncology Lung Cancer Patterns of care Utilisation |
| url | http://www.sciencedirect.com/science/article/pii/S2405630823001428 |
| work_keys_str_mv | AT julietacorral utilisationofradiotherapyinlungcancerascopingnarrativeliteraturereviewwithafocusontheintroductionofevidencebasedtherapeuticapproachesineurope AT josepmborras utilisationofradiotherapyinlungcancerascopingnarrativeliteraturereviewwithafocusontheintroductionofevidencebasedtherapeuticapproachesineurope AT yolandelievens utilisationofradiotherapyinlungcancerascopingnarrativeliteraturereviewwithafocusontheintroductionofevidencebasedtherapeuticapproachesineurope |