A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.
Main Authors: | Tianyi Zhang, Guifeng Wei, Christopher J. Millard, Roman Fischer, Rebecca Konietzny, Benedikt M. Kessler, John W. R. Schwabe, Neil Brockdorff |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06235-9 |
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