In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses
ABSTRACT: This study evaluated the in vitro antiviral activity of propolis and Baccharis sp. extracts on three animal herpesviruses (bovine, equine and swine). The propolis samples were produced by two species of bees. There was red and green propolis, which came from africanized Apis melifera, and...
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| Format: | Article |
| Language: | English |
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Instituto Biológico
2018-08-01
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| Series: | Arquivos do Instituto Biológico |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-16572018000100215&lng=en&tlng=en |
| _version_ | 1818618847736889344 |
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| author | Isabela Cristina Simoni Bruna Aguiar Aline Martineli de Araujo Navarro Rafael Martins Parreira Maria Judite Bittencourt Fernandes Alexandra Christine Helena Frankland Sawaya Oriana Aparecida Fávero |
| author_facet | Isabela Cristina Simoni Bruna Aguiar Aline Martineli de Araujo Navarro Rafael Martins Parreira Maria Judite Bittencourt Fernandes Alexandra Christine Helena Frankland Sawaya Oriana Aparecida Fávero |
| author_sort | Isabela Cristina Simoni |
| collection | DOAJ |
| description | ABSTRACT: This study evaluated the in vitro antiviral activity of propolis and Baccharis sp. extracts on three animal herpesviruses (bovine, equine and swine). The propolis samples were produced by two species of bees. There was red and green propolis, which came from africanized Apis melifera, and a third type obtained from a native bee species, Tetragonisca angustula (jatai). The Baccharis extracts were obtained from four different species: B. oblongifolia, B. burchellii, B. dracunculifolia and B. uncinella. The maximum non-toxic concentration of the extracts was determined when no visible morphological changes were observed on the cells. These non-toxic concentrations were used in the antiviral tests. Antiviral activity was evaluated using a reduction assay of the cytopathic effect, which calculated the difference between treated and control virus titer by statistical analysis. Red propolis was active against the three herpesviruses and green propolis showed inhibition against the equine and swine herpesviruses. Conversely, jataí propolis showed no antiviral activity. Most extracts coming from male and female individuals of all of the Baccharis species showed antiviral activity against bovine and swine herpesviruses. Only the extract of the female specimen of B. oblongifolia was an inhibitor against equine herpesvirus. |
| first_indexed | 2024-12-16T17:28:06Z |
| format | Article |
| id | doaj.art-505506b7157e43c6ba65782e0445f602 |
| institution | Directory Open Access Journal |
| issn | 1808-1657 |
| language | English |
| last_indexed | 2024-12-16T17:28:06Z |
| publishDate | 2018-08-01 |
| publisher | Instituto Biológico |
| record_format | Article |
| series | Arquivos do Instituto Biológico |
| spelling | doaj.art-505506b7157e43c6ba65782e0445f6022022-12-21T22:22:59ZengInstituto BiológicoArquivos do Instituto Biológico1808-16572018-08-0185010.1590/1808-1657000972016S1808-16572018000100215In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesvirusesIsabela Cristina SimoniBruna AguiarAline Martineli de Araujo NavarroRafael Martins ParreiraMaria Judite Bittencourt FernandesAlexandra Christine Helena Frankland SawayaOriana Aparecida FáveroABSTRACT: This study evaluated the in vitro antiviral activity of propolis and Baccharis sp. extracts on three animal herpesviruses (bovine, equine and swine). The propolis samples were produced by two species of bees. There was red and green propolis, which came from africanized Apis melifera, and a third type obtained from a native bee species, Tetragonisca angustula (jatai). The Baccharis extracts were obtained from four different species: B. oblongifolia, B. burchellii, B. dracunculifolia and B. uncinella. The maximum non-toxic concentration of the extracts was determined when no visible morphological changes were observed on the cells. These non-toxic concentrations were used in the antiviral tests. Antiviral activity was evaluated using a reduction assay of the cytopathic effect, which calculated the difference between treated and control virus titer by statistical analysis. Red propolis was active against the three herpesviruses and green propolis showed inhibition against the equine and swine herpesviruses. Conversely, jataí propolis showed no antiviral activity. Most extracts coming from male and female individuals of all of the Baccharis species showed antiviral activity against bovine and swine herpesviruses. Only the extract of the female specimen of B. oblongifolia was an inhibitor against equine herpesvirus.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-16572018000100215&lng=en&tlng=enantiviralprópolisBaccharisherpes vírus animal |
| spellingShingle | Isabela Cristina Simoni Bruna Aguiar Aline Martineli de Araujo Navarro Rafael Martins Parreira Maria Judite Bittencourt Fernandes Alexandra Christine Helena Frankland Sawaya Oriana Aparecida Fávero In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses Arquivos do Instituto Biológico antiviral própolis Baccharis herpes vírus animal |
| title | In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses |
| title_full | In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses |
| title_fullStr | In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses |
| title_full_unstemmed | In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses |
| title_short | In vitro antiviral activity of propolis and Baccharis sp. extracts on animal herpesviruses |
| title_sort | in vitro antiviral activity of propolis and baccharis sp extracts on animal herpesviruses |
| topic | antiviral própolis Baccharis herpes vírus animal |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-16572018000100215&lng=en&tlng=en |
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