miR-34a targets PAI-1 to regulate urinary microalbumin and renal function in hypertensive mice

miR-34a targets PAI-1 to regulate urinary microalbumin and renal function in hypertensive mice

Abstract Background The aim of the study is to investigate the effects of miR-34a targeted at PAI-1 on urinary microalbumin and renal function in hypertensive mice. Methods Twenty specific-pathogen-free (SPF) BPN/3J mice were selected in normal group, and 120 SPF BPH/2J mice were evenly divided into...

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Bibliographic Details
Main Authors: Ruitao Liu, Lihong Yang, Qingmin Wei
Format: Article
Language:English
Published: BMC 2020-03-01
Series:European Journal of Medical Research
Subjects:
miR-34a
PAI-1
Hypertension
Urinary microalbumin
Renal function
Online Access:http://link.springer.com/article/10.1186/s40001-020-00404-7

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http://link.springer.com/article/10.1186/s40001-020-00404-7

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