Evolutionary conservation of putative suicidality-related risk genes that produce diminished motivation corrected by clozapine, lithium and antidepressants

Evolutionary conservation of putative suicidality-related risk genes that produce diminished motivation corrected by clozapine, lithium and antidepressants

BackgroundGenome wide association studies (GWAS) and candidate gene analyses have identified genetic variants and genes that may increase the risk for suicidal thoughts and behaviors (STBs). Important unresolved issues surround these tentative risk variants such as the characteristics of the associa...

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Bibliographic Details
Main Authors: Titilade Ajayi, Alicia Thomas, Marko Nikolic, Lauryn Henderson, Alexa Zaheri, Donard S. Dwyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Psychiatry
Subjects:
antidepressants
C. elegans
clozapine
diminished motivation
lithium
suicide
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1341735/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1341735/full

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