The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion.

The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion.

Tail-anchored (TA) proteins represent a unique class of membrane proteins that contain a single C-terminal transmembrane helix. The post-translational insertion of the yeast TA proteins into the ER membrane requires the Golgi ER trafficking (GET) complex which contains Get1, Get2 and Get3. Get3 is a...

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Bibliographic Details
Main Authors: Junbin Hu, Jingzhi Li, Xinguo Qian, Vlad Denic, Bingdong Sha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2778870?pdf=render

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