CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS
Incidence of vulvar cancer in reproductive patients and peculiarities of clinical course of the disease have been studied. 839 vulvar cancer patients aged 20-90 years have been treated at Gynecology Department of Rostov Research Oncologic Institute within the latest 30 years. The reproducti...
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| Format: | Article |
| Language: | English |
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Bashkir State Medical University
2017-01-01
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| Series: | Креативная хирургия и онкология |
| Subjects: | |
| Online Access: | https://www.surgonco.ru/jour/article/view/137 |
| _version_ | 1797872412601090048 |
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| author | G. A. Nerodo E. M. Nepomnyashaya E. A. Nerodo |
| author_facet | G. A. Nerodo E. M. Nepomnyashaya E. A. Nerodo |
| author_sort | G. A. Nerodo |
| collection | DOAJ |
| description | Incidence of vulvar cancer in reproductive patients and peculiarities of clinical course of the disease have been studied. 839 vulvar cancer patients aged 20-90 years have been treated at Gynecology Department of Rostov Research Oncologic Institute within the latest 30 years. The reproductive group (20-50 years of age) included 64 patients (7,6%). Early stages of vulvar cancer in the reproductive group were diagnosed more often than in elderly patients. Neurodystrophic changes of vulvar in young patients were much rarely observed in comparison with elderly patients. Almost 80% of patients under 40 years of age had human papilloma virus; in the group of 41-50 years of age – 50%; whereas in the elderly group contamination with human papilloma virus was observed only in single cases – 0,48%. Organ-sparing operations performed by strict individual approach are possible in the group of young patients. Vulvar cancer, in particular with advanced malignant process, requires complex treatment including neoadjuvant and multi-course adjuvant chemotherapy. Recurrent disease in reproductive patients is observed less frequent than in elderly patients. Chemotherapy is appropriate in cases of recurrent disease in order to improve operability. |
| first_indexed | 2024-04-10T00:59:27Z |
| format | Article |
| id | doaj.art-505ca1d8be0d406fa8f3a29c20b53333 |
| institution | Directory Open Access Journal |
| issn | 2307-0501 2076-3093 |
| language | English |
| last_indexed | 2024-04-10T00:59:27Z |
| publishDate | 2017-01-01 |
| publisher | Bashkir State Medical University |
| record_format | Article |
| series | Креативная хирургия и онкология |
| spelling | doaj.art-505ca1d8be0d406fa8f3a29c20b533332023-03-13T10:01:06ZengBashkir State Medical UniversityКреативная хирургия и онкология2307-05012076-30932017-01-0103616610.24060/2076-3093-2012-0-3-61-66137CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTSG. A. Nerodo0E. M. Nepomnyashaya1E. A. Nerodo2Ростовский Научно-исследовательский онкологический институтРостовский Научно-исследовательский онкологический институтРостовский Научно-исследовательский онкологический институтIncidence of vulvar cancer in reproductive patients and peculiarities of clinical course of the disease have been studied. 839 vulvar cancer patients aged 20-90 years have been treated at Gynecology Department of Rostov Research Oncologic Institute within the latest 30 years. The reproductive group (20-50 years of age) included 64 patients (7,6%). Early stages of vulvar cancer in the reproductive group were diagnosed more often than in elderly patients. Neurodystrophic changes of vulvar in young patients were much rarely observed in comparison with elderly patients. Almost 80% of patients under 40 years of age had human papilloma virus; in the group of 41-50 years of age – 50%; whereas in the elderly group contamination with human papilloma virus was observed only in single cases – 0,48%. Organ-sparing operations performed by strict individual approach are possible in the group of young patients. Vulvar cancer, in particular with advanced malignant process, requires complex treatment including neoadjuvant and multi-course adjuvant chemotherapy. Recurrent disease in reproductive patients is observed less frequent than in elderly patients. Chemotherapy is appropriate in cases of recurrent disease in order to improve operability.https://www.surgonco.ru/jour/article/view/137рак вульвымолодой возрастклиническое течение |
| spellingShingle | G. A. Nerodo E. M. Nepomnyashaya E. A. Nerodo CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS Креативная хирургия и онкология рак вульвы молодой возраст клиническое течение |
| title | CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS |
| title_full | CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS |
| title_fullStr | CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS |
| title_full_unstemmed | CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS |
| title_short | CLINICAL COURSE OF VULVAR CANCER IN REPRODUCTIVE PATIENTS |
| title_sort | clinical course of vulvar cancer in reproductive patients |
| topic | рак вульвы молодой возраст клиническое течение |
| url | https://www.surgonco.ru/jour/article/view/137 |
| work_keys_str_mv | AT ganerodo clinicalcourseofvulvarcancerinreproductivepatients AT emnepomnyashaya clinicalcourseofvulvarcancerinreproductivepatients AT eanerodo clinicalcourseofvulvarcancerinreproductivepatients |