RNA binding protein PUM2 promotes IL-1β-induced apoptosis of chondrocytes via regulating FOXO3 expression

RNA binding protein PUM2 promotes IL-1β-induced apoptosis of chondrocytes via regulating FOXO3 expression

Objective: RNA-binding proteins (RBPs) have been recently proven to be involved in the pathogenesis of several diseases. However, few studies elaborated RBPs in regulating osteoarthritis. This study aims to define the function and mechanism of RBPs-PUM2 in chondrocyte apoptosis during osteoarthritis...

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Bibliographic Details
Main Authors: Du Wang, ZhiLi Zhang, Xili Li, Ling He
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Apoptosis
FOXO3
Chondrocyte
PUM2
Osteoarthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024011113

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