Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study

Background: Nonablative lasers are popular alternatives for atrophic acne scar treatment in Asia. Objectives: We aimed to compare the efficacy and safety between 1550-nm nonablative fractional laser (NAFL) and 755-nm picosecond laser with diffractive lens array (DLA) in Asian patients. Methods: Twen...

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Main Authors: Mao-Ying Lin, Sindy Hu, Chrang-Shi Lin, Wen-Hung Chung
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Dermatologica Sinica
Subjects:
Online Access:http://www.dermsinica.org/article.asp?issn=1027-8117;year=2021;volume=39;issue=4;spage=186;epage=191;aulast=Lin
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author Mao-Ying Lin
Sindy Hu
Chrang-Shi Lin
Wen-Hung Chung
author_facet Mao-Ying Lin
Sindy Hu
Chrang-Shi Lin
Wen-Hung Chung
author_sort Mao-Ying Lin
collection DOAJ
description Background: Nonablative lasers are popular alternatives for atrophic acne scar treatment in Asia. Objectives: We aimed to compare the efficacy and safety between 1550-nm nonablative fractional laser (NAFL) and 755-nm picosecond laser with diffractive lens array (DLA) in Asian patients. Methods: Twenty-three patients with atrophic acne scars received three sessions of split-face treatment with 1550-nm NAFL on one side and 755-nm picosecond laser with DLA on the other side. Sessions were applied at 8-week interval. Blinded dermatologists assessed efficacy through baseline and follow-up photographs. Results: A greater improvement in atrophic facial acne scars was observed on the 1550-nm NAFL side than on the 755-nm picosecond laser side (P < 0.05). Pain was significantly more severe on the 1550-nm NAFL side than the 755-nm picosecond laser side (P < 0.05). Adverse effects on the 1550-nm NAFL side included prolonged erythema, acneiform eruptions, superficial crusting, and postinflammatory hyperpigmentation. Only transient erythema was observed on the 755-nm picosecond laser side. Conclusion: Although the 1550-nm NAFL showed superior efficacy to the 755-nm picosecond laser with DLA for the treatment of atrophic facial acne scars, the latter was associated with fewer adverse effects and may be the best choice for those who request “little-to-no down-time” treatments.
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spelling doaj.art-5063e78b68b44846b9cdcc0a89f477302022-12-21T17:22:07ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172223-330X2021-01-0139418619110.4103/ds.ds_38_21Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical studyMao-Ying LinSindy HuChrang-Shi LinWen-Hung ChungBackground: Nonablative lasers are popular alternatives for atrophic acne scar treatment in Asia. Objectives: We aimed to compare the efficacy and safety between 1550-nm nonablative fractional laser (NAFL) and 755-nm picosecond laser with diffractive lens array (DLA) in Asian patients. Methods: Twenty-three patients with atrophic acne scars received three sessions of split-face treatment with 1550-nm NAFL on one side and 755-nm picosecond laser with DLA on the other side. Sessions were applied at 8-week interval. Blinded dermatologists assessed efficacy through baseline and follow-up photographs. Results: A greater improvement in atrophic facial acne scars was observed on the 1550-nm NAFL side than on the 755-nm picosecond laser side (P < 0.05). Pain was significantly more severe on the 1550-nm NAFL side than the 755-nm picosecond laser side (P < 0.05). Adverse effects on the 1550-nm NAFL side included prolonged erythema, acneiform eruptions, superficial crusting, and postinflammatory hyperpigmentation. Only transient erythema was observed on the 755-nm picosecond laser side. Conclusion: Although the 1550-nm NAFL showed superior efficacy to the 755-nm picosecond laser with DLA for the treatment of atrophic facial acne scars, the latter was associated with fewer adverse effects and may be the best choice for those who request “little-to-no down-time” treatments.http://www.dermsinica.org/article.asp?issn=1027-8117;year=2021;volume=39;issue=4;spage=186;epage=191;aulast=Linatrophic acne scarfractional laserpicosecond laser
spellingShingle Mao-Ying Lin
Sindy Hu
Chrang-Shi Lin
Wen-Hung Chung
Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study
Dermatologica Sinica
atrophic acne scar
fractional laser
picosecond laser
title Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study
title_full Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study
title_fullStr Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study
title_full_unstemmed Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study
title_short Comparison of 1550-nm nonablative fractional laser versus 755-nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin: A prospective randomized split-face clinical study
title_sort comparison of 1550 nm nonablative fractional laser versus 755 nm picosecond laser with diffractive lens array for atrophic facial acne scars in asian skin a prospective randomized split face clinical study
topic atrophic acne scar
fractional laser
picosecond laser
url http://www.dermsinica.org/article.asp?issn=1027-8117;year=2021;volume=39;issue=4;spage=186;epage=191;aulast=Lin
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