Intra-Arterially Delivered Mesenchymal Stem Cells Are Not Detected in the Brain Parenchyma in an Alzheimer's Disease Mouse Model.
Mesenchymal stem cells (MSCs) have a promising role as a therapeutic agent for neurodegenerative diseases such as Alzheimer's disease (AD). Prior studies suggested that intra-arterially administered MSCs are engrafted into the brain in stroke or traumatic brain injury (TBI) animal models. Howev...
Main Authors: | Na Kyung Lee, Jehoon Yang, Eun Hyuk Chang, Sang Eon Park, Jeongmin Lee, Soo Jin Choi, Wonil Oh, Jong Wook Chang, Duk L Na |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4874686?pdf=render |
Similar Items
-
Exploring the Potential of Mesenchymal Stem Cell-Based Therapy in Mouse Models of Vascular Cognitive Impairment
by: Na Kyung Lee, et al.
Published: (2020-08-01) -
Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells
by: Na-Hee Lee, et al.
Published: (2020-09-01) -
Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial
by: Hee Jin Kim, et al.
Published: (2021-09-01) -
A Comparison of Immune Responses Exerted Following Syngeneic, Allogeneic, and Xenogeneic Transplantation of Mesenchymal Stem Cells into the Mouse Brain
by: Jung Won Hwang, et al.
Published: (2020-04-01) -
Magnetic resonance imaging analysis predicts nanoparticle concentration delivered to the brain parenchyma
by: Michael Plaksin, et al.
Published: (2022-09-01)