New approaches for characterization of the genetic stability of vaccine cell lines
The genetic stability of cell lines is a critical analytical attribute required to demonstrate the quality of cells over time. During cell passage, mutations can arise in the genomic DNA, potentially leading to changes in the final vaccine product. The identity and integrity of master cell banks, ex...
Main Authors: | Siemon Ng, Lucy Gisonni-Lex, Ali Azizi |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-07-01
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Series: | Human Vaccines & Immunotherapeutics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/21645515.2017.1295191 |
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