Exploring the conformational diversity of proteins

An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.

Bibliographic Details
Main Authors: Avner Schlessinger, Massimiliano Bonomi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/78549
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author Avner Schlessinger
Massimiliano Bonomi
author_facet Avner Schlessinger
Massimiliano Bonomi
author_sort Avner Schlessinger
collection DOAJ
description An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
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spelling doaj.art-506be495206741648b26b9c49729cdd12022-12-22T02:02:12ZengeLife Sciences Publications LtdeLife2050-084X2022-04-011110.7554/eLife.78549Exploring the conformational diversity of proteinsAvner Schlessinger0https://orcid.org/0000-0003-4007-7814Massimiliano Bonomi1https://orcid.org/0000-0002-7321-0004Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, United StatesDepartment of Structural Biology and Chemistry, Institut Pasteur, Université Paris Cité, Paris, FranceAn artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.https://elifesciences.org/articles/78549protein structure predictiontransportersG-protein coupled receptorsconformational dynamicstransmembrane proteinartificial intelligence
spellingShingle Avner Schlessinger
Massimiliano Bonomi
Exploring the conformational diversity of proteins
eLife
protein structure prediction
transporters
G-protein coupled receptors
conformational dynamics
transmembrane protein
artificial intelligence
title Exploring the conformational diversity of proteins
title_full Exploring the conformational diversity of proteins
title_fullStr Exploring the conformational diversity of proteins
title_full_unstemmed Exploring the conformational diversity of proteins
title_short Exploring the conformational diversity of proteins
title_sort exploring the conformational diversity of proteins
topic protein structure prediction
transporters
G-protein coupled receptors
conformational dynamics
transmembrane protein
artificial intelligence
url https://elifesciences.org/articles/78549
work_keys_str_mv AT avnerschlessinger exploringtheconformationaldiversityofproteins
AT massimilianobonomi exploringtheconformationaldiversityofproteins