Synthesis and biological evaluation of ciprofloxacin – 1,2,3-triazole hybrids as antitumor, antibacterial, and antioxidant agents

Synthesis and biological evaluation of ciprofloxacin – 1,2,3-triazole hybrids as antitumor, antibacterial, and antioxidant agents

Six novel ciprofloxacin-1,2,3-triazole hybrids (6a-f) were synthesized via click reaction, by reacting of methyl 1-cyclopropyl-6-fluoro-4-oxo-7-(4-(3-oxobutanoyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate (5) with various aryl azides (9a-f). The new compounds were characterized using High-Re...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Samir Al-Taweel, Yousef Al-Saraireh, Salah Al-Trawneh, Solhe Alshahateet, Rakan Al- Tarawneh, Nadaa Ayed, Mohammad Alkhojah, Wisam AL-Khaboori, Wael Zereini, Omar Al-Qaralleh
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Elsevier 2023-12-01
Σειρά:	Heliyon
Θέματα:	Anti-tumor Ciprofloxacin 1,2,3-Triazoles Huisgen 1,3-dipolar cycloaddition Non-small cell lung cancer Glioblastoma
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2405844023098006

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