The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children
The neural mechanisms underlying susceptibility to eating more in response to large portions (i.e., the portion size effect) remain unclear. Thus, the present study examined how neural responses to portion size relate to changes in weight and energy consumed as portions increase. Associations were e...
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| Format: | Article |
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MDPI AG
2024-03-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/5/738 |
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| author | Bari A. Fuchs Alaina L. Pearce Barbara J. Rolls Stephen J. Wilson Emma J. Rose Charles F. Geier Hugh Garavan Kathleen L. Keller |
| author_facet | Bari A. Fuchs Alaina L. Pearce Barbara J. Rolls Stephen J. Wilson Emma J. Rose Charles F. Geier Hugh Garavan Kathleen L. Keller |
| author_sort | Bari A. Fuchs |
| collection | DOAJ |
| description | The neural mechanisms underlying susceptibility to eating more in response to large portions (i.e., the portion size effect) remain unclear. Thus, the present study examined how neural responses to portion size relate to changes in weight and energy consumed as portions increase. Associations were examined across brain regions traditionally implicated in appetite control (i.e., an appetitive network) as well as the cerebellum, which has recently been implicated in appetite-related processes. Children without obesity (i.e., BMI-for-age-and-sex percentile < 90; N = 63; 55% female) viewed images of larger and smaller portions of food during fMRI and, in separate sessions, ate four meals that varied in portion size. Individual-level linear and quadratic associations between intake (kcal, grams) and portion size (i.e., portion size slopes) were estimated. The response to portion size in cerebellar lobules IV–VI was associated with the quadratic portion size slope estimated from gram intake; a greater response to images depicting smaller compared to larger portions was associated with steeper increases in intake with increasing portion sizes. Within the appetitive network, neural responses were not associated with portion size slopes. A decreased cerebellar response to larger amounts of food may increase children’s susceptibility to overeating when excessively large portions are served. |
| first_indexed | 2024-04-25T00:22:03Z |
| format | Article |
| id | doaj.art-506eb514ad0a4961ba7f66421302f239 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-04-25T00:22:03Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-506eb514ad0a4961ba7f66421302f2392024-03-12T16:52:25ZengMDPI AGNutrients2072-66432024-03-0116573810.3390/nu16050738The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in ChildrenBari A. Fuchs0Alaina L. Pearce1Barbara J. Rolls2Stephen J. Wilson3Emma J. Rose4Charles F. Geier5Hugh Garavan6Kathleen L. Keller7Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USADepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USADepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USADepartment of Psychology, The Pennsylvania State University, University Park, PA 16802, USADepartment of Psychology, The Pennsylvania State University, University Park, PA 16802, USAHuman Development and Family Science, University of Georgia, Athens, GA 31793, USADepartment of Psychological Sciences, University of Vermont, Burlington, VT 05405, USADepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USAThe neural mechanisms underlying susceptibility to eating more in response to large portions (i.e., the portion size effect) remain unclear. Thus, the present study examined how neural responses to portion size relate to changes in weight and energy consumed as portions increase. Associations were examined across brain regions traditionally implicated in appetite control (i.e., an appetitive network) as well as the cerebellum, which has recently been implicated in appetite-related processes. Children without obesity (i.e., BMI-for-age-and-sex percentile < 90; N = 63; 55% female) viewed images of larger and smaller portions of food during fMRI and, in separate sessions, ate four meals that varied in portion size. Individual-level linear and quadratic associations between intake (kcal, grams) and portion size (i.e., portion size slopes) were estimated. The response to portion size in cerebellar lobules IV–VI was associated with the quadratic portion size slope estimated from gram intake; a greater response to images depicting smaller compared to larger portions was associated with steeper increases in intake with increasing portion sizes. Within the appetitive network, neural responses were not associated with portion size slopes. A decreased cerebellar response to larger amounts of food may increase children’s susceptibility to overeating when excessively large portions are served.https://www.mdpi.com/2072-6643/16/5/738fMRIportion sizefood cue reactivityeating behavior |
| spellingShingle | Bari A. Fuchs Alaina L. Pearce Barbara J. Rolls Stephen J. Wilson Emma J. Rose Charles F. Geier Hugh Garavan Kathleen L. Keller The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children Nutrients fMRI portion size food cue reactivity eating behavior |
| title | The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children |
| title_full | The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children |
| title_fullStr | The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children |
| title_full_unstemmed | The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children |
| title_short | The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children |
| title_sort | cerebellar response to visual portion size cues is associated with the portion size effect in children |
| topic | fMRI portion size food cue reactivity eating behavior |
| url | https://www.mdpi.com/2072-6643/16/5/738 |
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