Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs

Type III interferons (IFNs) (or IFN-λ) are the latest addition to the IFN family. Even though they share little protein homology with type I IFN, both exhibit remarkable functional similarities: each can be induced in response to viral infections, and both lead to Janus kinases (JAK) and signal tran...

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Bibliographic Details
Main Authors: Ivan Zanoni, Francesca Granucci, Achille Broggi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
interferon lambda
dendritic cells
neutrophils
natural killer cells
type III interferon
viral infection
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01661/full

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