Inference of genetic relatedness between viral quasispecies from sequencing data

Inference of genetic relatedness between viral quasispecies from sequencing data

Abstract Background RNA viruses such as HCV and HIV mutate at extremely high rates, and as a result, they exist in infected hosts as populations of genetically related variants. Recent advances in sequencing technologies make possible to identify such populations at great depth. In particular, these...

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Bibliographic Details
Main Authors: Olga Glebova, Sergey Knyazev, Andrew Melnyk, Alexander Artyomenko, Yury Khudyakov, Alex Zelikovsky, Pavel Skums
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Genetic relatedness
Transmission networks
Outbreaks investigations
Simulation
Clustering
Online Access:http://link.springer.com/article/10.1186/s12864-017-4274-5

Internet

http://link.springer.com/article/10.1186/s12864-017-4274-5

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