Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus–infected mice
Antiviral immunity often requires CD8+ cytotoxic T lymphocytes (CTLs) that actively migrate and search for virus-infected targets. Regulatory T cells (Tregs) have been shown to suppress CTL responses, but it is not known whether this is also mediated by effects on CTL motility. Here, we used intravi...
Main Authors: | Daniela Mittermüller, Lucas Otto, Zoë Long, Andreas Kraus, Alexander Beer, Anja Hasenberg, Gennadiy Zelinskyy, Jaana Westmeier, Kim J. Hasenkrug, Ulf Dittmer, Matthias Gunzer |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2023-07-01
|
Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.167482 |
Similar Items
-
Loss of histone reader Phf7 leads to immune pathways activation via endogenous retroviruses during spermiogenesis
by: Jianxing Cheng, et al.
Published: (2023-11-01) -
The impact of innate immune cells on immunopathology in dengue
by: Howells, A
Published: (2014) -
Human T cells efficiently control RSV infection
by: Chandrav De, et al.
Published: (2023-06-01) -
Oncolytic alphavirus replicons mediated recruitment and activation of T cells
by: Darshak K. Bhatt, et al.
Published: (2024-03-01) -
Characterizing infection of B cells with wild-type and vaccine strains of measles virus
by: Logan Melot, et al.
Published: (2023-10-01)