Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae)
Background: Flubendiamide, comparatively a new pesticide designed to eradicate lepidopteran insect pests is known to have low risk to birds, mammals, fish, algae, honey bees, non-target arthropods, earthworms, soil macro- and micro-organisms, non-target plants as well as sewage treatment organisms;...
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| Format: | Article |
| Language: | English |
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Arak University of Medical Sciences
2018-04-01
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| Series: | Iranian Journal of Toxicology |
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| Online Access: | https://ijt.arakmu.ac.ir/article-1-628-en.pdf |
| _version_ | 1811250110235934720 |
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| author | Saurabh Sarkar Prem Rajak Sumedha Roy* |
| author_facet | Saurabh Sarkar Prem Rajak Sumedha Roy* |
| author_sort | Saurabh Sarkar |
| collection | DOAJ |
| description | Background: Flubendiamide, comparatively a new pesticide designed to eradicate lepidopteran insect pests is known to have low risk to birds, mammals, fish, algae, honey bees, non-target arthropods, earthworms, soil macro- and micro-organisms, non-target plants as well as sewage treatment organisms; however, the risk assessment for aquatic invertebrates from metabolite could not be finalized with available data.
Methods: Different concentrations of flubendiamide (TATA TAKUMI®, Rallis, India) were introduced to larvae, pupae, and adult flies. A wide range of comparatively higher concentrations was selected for acute LC50 than chronic LC50 due to their exposure duration. Furthermore, relatively lower concentrations were introduced to larvae for assessment of emergence.
Results: At chronic exposure, the effect-concentration relationship exhibited a linear response when adult emergence was considered in Drosophila melanogaster. When acute LC50 of flubendiamide in 3rd instar larvae was compared with the chronic LC50 then it was seen to be approximately 21 fold higher whereas chronic LC50 for adult flies was nearly 19 times less than the adult acute LC50. Similarly, adult emergence was seen to lower by 91.95% at 1500 µg/mL concentration. The chronic LC50 of the flubendiamide in Drosophila was approximately 170303 times more than the reported No Observed Effect Concentration (NOEC).
Conclusion: Hence, the chemical, flubendiamide can induce its effects at very low concentration, far below the lethal ones. Thus, the study is of relevance for the non-target insects as well as the insect dependent organisms. |
| first_indexed | 2024-04-12T15:59:13Z |
| format | Article |
| id | doaj.art-5088bac282e74719badba2efff509ba7 |
| institution | Directory Open Access Journal |
| issn | 2008-2967 2251-9459 |
| language | English |
| last_indexed | 2024-04-12T15:59:13Z |
| publishDate | 2018-04-01 |
| publisher | Arak University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Toxicology |
| spelling | doaj.art-5088bac282e74719badba2efff509ba72022-12-22T03:26:15ZengArak University of Medical SciencesIranian Journal of Toxicology2008-29672251-94592018-04-011234550Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae)Saurabh Sarkar 0Prem Rajak 1Sumedha Roy*2Department of Zoology, The University of Burdwan, Burdwan, India.Department of Zoology, ABN Seal College, Cooch Behar, India.Department of Zoology, the University of Burdwan, Burdwan, India. *Corresponding Author: E-mail: roysumedha@gmail.comBackground: Flubendiamide, comparatively a new pesticide designed to eradicate lepidopteran insect pests is known to have low risk to birds, mammals, fish, algae, honey bees, non-target arthropods, earthworms, soil macro- and micro-organisms, non-target plants as well as sewage treatment organisms; however, the risk assessment for aquatic invertebrates from metabolite could not be finalized with available data. Methods: Different concentrations of flubendiamide (TATA TAKUMI®, Rallis, India) were introduced to larvae, pupae, and adult flies. A wide range of comparatively higher concentrations was selected for acute LC50 than chronic LC50 due to their exposure duration. Furthermore, relatively lower concentrations were introduced to larvae for assessment of emergence. Results: At chronic exposure, the effect-concentration relationship exhibited a linear response when adult emergence was considered in Drosophila melanogaster. When acute LC50 of flubendiamide in 3rd instar larvae was compared with the chronic LC50 then it was seen to be approximately 21 fold higher whereas chronic LC50 for adult flies was nearly 19 times less than the adult acute LC50. Similarly, adult emergence was seen to lower by 91.95% at 1500 µg/mL concentration. The chronic LC50 of the flubendiamide in Drosophila was approximately 170303 times more than the reported No Observed Effect Concentration (NOEC). Conclusion: Hence, the chemical, flubendiamide can induce its effects at very low concentration, far below the lethal ones. Thus, the study is of relevance for the non-target insects as well as the insect dependent organisms.https://ijt.arakmu.ac.ir/article-1-628-en.pdfDrosophila MelanogasterEmergenceFlubendiamideLC50 |
| spellingShingle | Saurabh Sarkar Prem Rajak Sumedha Roy* Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae) Iranian Journal of Toxicology Drosophila Melanogaster Emergence Flubendiamide LC50 |
| title | Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae) |
| title_full | Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae) |
| title_fullStr | Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae) |
| title_full_unstemmed | Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae) |
| title_short | Toxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae) |
| title_sort | toxicological evaluation of a new lepidopteran insecticide flubendiamide in non target drosophila melanogaster meigen diptera drosophilidae |
| topic | Drosophila Melanogaster Emergence Flubendiamide LC50 |
| url | https://ijt.arakmu.ac.ir/article-1-628-en.pdf |
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