Cardiometabolic Risk Factors in Adolescent Women’s Health

Despite significant advances in diagnosis and treatment, cardiovascular disease (CVD) remains a major cause of mortality and morbidity for men and women. While disease rates are somewhat declining for men, risk for women, and earlier age at onset, is increasing. As with many common conditions, preve...

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Main Author: Marcelle Cedars
Format: Article
Language:English
Published: World Scientific Publishing 2023-12-01
Series:Fertility & Reproduction
Online Access:https://www.worldscientific.com/doi/10.1142/S2661318223741139
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author Marcelle Cedars
author_facet Marcelle Cedars
author_sort Marcelle Cedars
collection DOAJ
description Despite significant advances in diagnosis and treatment, cardiovascular disease (CVD) remains a major cause of mortality and morbidity for men and women. While disease rates are somewhat declining for men, risk for women, and earlier age at onset, is increasing. As with many common conditions, prevention and/or early intervention for those at risk, leads to better long-term outcome than treatment and secondary prevention. In order to better achieve reduction in disease in adulthood, we need to recognize critical periods of vulnerability for disease development. These include broadly the maternal environment, but also early childhood and adolescence, two periods with rapid growth and development, where environmental “insults” may have long-lasting impact. As suggested by the Developmental Origins of Adult Disease (DoAD) and the Dutch famine studies, the in-utero environment is a critical window. And maternal health leading into pregnancy, maternal health during pregnancy and any potential environmental exposures, will all impact childhood and likely adult health. Careful studies across childhood, particularly with emphasis on BMI and BMI trajectories and adverse social situations and abuse, are producing informative data regarding the importance of this critical time-period for both awareness and intervention. And, interventions, as simple as improving diet and sleep, may improve our ability for early intervention in simple ways to improve women’s health and longevity.
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spelling doaj.art-508ea010a5984a6da0d40568912cba022024-03-28T07:54:19ZengWorld Scientific PublishingFertility & Reproduction2661-31822661-31742023-12-01050429929910.1142/S2661318223741139Cardiometabolic Risk Factors in Adolescent Women’s HealthMarcelle Cedars0Professor and Director of the Division of Reproductive Endocrinology, UCSF Health, USADespite significant advances in diagnosis and treatment, cardiovascular disease (CVD) remains a major cause of mortality and morbidity for men and women. While disease rates are somewhat declining for men, risk for women, and earlier age at onset, is increasing. As with many common conditions, prevention and/or early intervention for those at risk, leads to better long-term outcome than treatment and secondary prevention. In order to better achieve reduction in disease in adulthood, we need to recognize critical periods of vulnerability for disease development. These include broadly the maternal environment, but also early childhood and adolescence, two periods with rapid growth and development, where environmental “insults” may have long-lasting impact. As suggested by the Developmental Origins of Adult Disease (DoAD) and the Dutch famine studies, the in-utero environment is a critical window. And maternal health leading into pregnancy, maternal health during pregnancy and any potential environmental exposures, will all impact childhood and likely adult health. Careful studies across childhood, particularly with emphasis on BMI and BMI trajectories and adverse social situations and abuse, are producing informative data regarding the importance of this critical time-period for both awareness and intervention. And, interventions, as simple as improving diet and sleep, may improve our ability for early intervention in simple ways to improve women’s health and longevity.https://www.worldscientific.com/doi/10.1142/S2661318223741139
spellingShingle Marcelle Cedars
Cardiometabolic Risk Factors in Adolescent Women’s Health
Fertility & Reproduction
title Cardiometabolic Risk Factors in Adolescent Women’s Health
title_full Cardiometabolic Risk Factors in Adolescent Women’s Health
title_fullStr Cardiometabolic Risk Factors in Adolescent Women’s Health
title_full_unstemmed Cardiometabolic Risk Factors in Adolescent Women’s Health
title_short Cardiometabolic Risk Factors in Adolescent Women’s Health
title_sort cardiometabolic risk factors in adolescent women s health
url https://www.worldscientific.com/doi/10.1142/S2661318223741139
work_keys_str_mv AT marcellecedars cardiometabolicriskfactorsinadolescentwomenshealth