GRK2–YAP signaling is implicated in pulmonary arterial hypertension development

Abstract. Background:. Pulmonary arterial hypertension (PAH) is characterized by excessive proliferation of small pulmonary arterial vascular smooth muscle cells (PASMCs), endothelial dysfunction, and extracellular matrix remodeling. G protein-coupled receptor kinase 2 (GRK2) plays an important rol...

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Bibliographic Details
Main Authors: Peng Ye, Yunfei Deng, Yue Gu, Pengfei Liu, Jie Luo, Jiangqin Pu, Jingyu Chen, Yu Huang, Nanping Wang, Yong Ji, Shaoliang Chen, Rongman Jia, Xiuyuan Hao
Format: Article
Language:English
Published: Wolters Kluwer 2024-04-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002946