Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty
Objectives: This study was to compare the effects of different local analgesia protocols on osteoarthritis patients undergoing total knee arthroplasty (TKA). Methods: Medical records of 148 osteoarthritis patients who underwent unilateral TKA between October 2016 and October 2017 in our hospital wer...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-03-01
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| Series: | Brazilian Journal of Anesthesiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0104001421000634 |
| _version_ | 1811200563858112512 |
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| author | Yang Wang Guoqing Li Muhtar Momin Baochao Ji Li Cao Aishajiang Aisikeerbayi |
| author_facet | Yang Wang Guoqing Li Muhtar Momin Baochao Ji Li Cao Aishajiang Aisikeerbayi |
| author_sort | Yang Wang |
| collection | DOAJ |
| description | Objectives: This study was to compare the effects of different local analgesia protocols on osteoarthritis patients undergoing total knee arthroplasty (TKA). Methods: Medical records of 148 osteoarthritis patients who underwent unilateral TKA between October 2016 and October 2017 in our hospital were retrospectively analyzed. All these patients were divided into three groups according to the pain management protocol (morphine, morphine + cocktail [100 mg ropivacaine, 10 mg morphine, and 30 mL 0.9% sodium chloride solution containing 2 mL betamethasone (4 mg)], or cocktail). The postoperative visual analog scale (VAS) score, muscle strength, and complications were compared between the groups. Results: At 6 and 12 hours post-operation, the VAS score in group C was significantly higher than that in group A or group B. In addition, the muscle (quadriceps femoris) strength score of group C (3.7 ± 2.8) was significantly higher than that in groups A and B at 6 and 12 hours post-operation. The VAS score and muscle strength score showed no significant differences among the three groups at 24 and 36 hours post-operation. The time of postoperative first void of group C was significantly shorter than that of groups A and B. Groups A or B had a significantly higher incidence of nausea and emesis compared with group C. The incidence of pruritus was higher in groups A or B than that in group C. Conclusion: Epidural anesthesia combined with local analgesic cocktail injection is a preferable effective multimodal analgesia for TKA. |
| first_indexed | 2024-04-12T02:05:36Z |
| format | Article |
| id | doaj.art-50938bcee2c04652b111f2ee8c21ade1 |
| institution | Directory Open Access Journal |
| issn | 0104-0014 |
| language | English |
| last_indexed | 2024-04-12T02:05:36Z |
| publishDate | 2022-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Anesthesiology |
| spelling | doaj.art-50938bcee2c04652b111f2ee8c21ade12022-12-22T03:52:32ZengElsevierBrazilian Journal of Anesthesiology0104-00142022-03-01722267273Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplastyYang Wang0Guoqing Li1Muhtar Momin2Baochao Ji3Li Cao4Aishajiang Aisikeerbayi5The First Affiliated Hospital of Xinjiang Medical University, Department of Orthopedics, Urumqi, ChinaThe First Affiliated Hospital of Xinjiang Medical University, Department of Orthopedics, Urumqi, ChinaThe First Affiliated Hospital of Xinjiang Medical University, Department of Orthopedics, Urumqi, ChinaThe First Affiliated Hospital of Xinjiang Medical University, Department of Orthopedics, Urumqi, ChinaThe First Affiliated Hospital of Xinjiang Medical University, Department of Orthopedics, Urumqi, China; Corresponding author.Yili Xinhua Hospital, Department of Orthopedics, Yining, ChinaObjectives: This study was to compare the effects of different local analgesia protocols on osteoarthritis patients undergoing total knee arthroplasty (TKA). Methods: Medical records of 148 osteoarthritis patients who underwent unilateral TKA between October 2016 and October 2017 in our hospital were retrospectively analyzed. All these patients were divided into three groups according to the pain management protocol (morphine, morphine + cocktail [100 mg ropivacaine, 10 mg morphine, and 30 mL 0.9% sodium chloride solution containing 2 mL betamethasone (4 mg)], or cocktail). The postoperative visual analog scale (VAS) score, muscle strength, and complications were compared between the groups. Results: At 6 and 12 hours post-operation, the VAS score in group C was significantly higher than that in group A or group B. In addition, the muscle (quadriceps femoris) strength score of group C (3.7 ± 2.8) was significantly higher than that in groups A and B at 6 and 12 hours post-operation. The VAS score and muscle strength score showed no significant differences among the three groups at 24 and 36 hours post-operation. The time of postoperative first void of group C was significantly shorter than that of groups A and B. Groups A or B had a significantly higher incidence of nausea and emesis compared with group C. The incidence of pruritus was higher in groups A or B than that in group C. Conclusion: Epidural anesthesia combined with local analgesic cocktail injection is a preferable effective multimodal analgesia for TKA.http://www.sciencedirect.com/science/article/pii/S0104001421000634Epidural anesthesiaMorphineCocktail injectionTotal knee arthroplasty |
| spellingShingle | Yang Wang Guoqing Li Muhtar Momin Baochao Ji Li Cao Aishajiang Aisikeerbayi Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty Brazilian Journal of Anesthesiology Epidural anesthesia Morphine Cocktail injection Total knee arthroplasty |
| title | Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty |
| title_full | Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty |
| title_fullStr | Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty |
| title_full_unstemmed | Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty |
| title_short | Comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty |
| title_sort | comparison of different local analgesia protocols in postoperative pain management after total knee arthroplasty |
| topic | Epidural anesthesia Morphine Cocktail injection Total knee arthroplasty |
| url | http://www.sciencedirect.com/science/article/pii/S0104001421000634 |
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