Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells
Highlights HM-Exos were successfully isolated using the exosome extraction kit. The size and shape of HM-Exos were analyzed using DLS, SEM, and TEM. HM-Exos improved the migration potential of LPS-exposed HDPSCs. HM-Exos reduced the expression of inflammatory cytokines such as TNF-α, IL-1β, and IL-6...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-02-01
|
| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12903-023-02796-4 |
| _version_ | 1797863324923199488 |
|---|---|
| author | Ehsaneh Azaryan Samira Karbasi Mansoore Saharkhiz Mohammad Yahya Hanafi-Bojd Asghar Zarban Fariba Emadian Razavi Mohsen Naseri |
| author_facet | Ehsaneh Azaryan Samira Karbasi Mansoore Saharkhiz Mohammad Yahya Hanafi-Bojd Asghar Zarban Fariba Emadian Razavi Mohsen Naseri |
| author_sort | Ehsaneh Azaryan |
| collection | DOAJ |
| description | Highlights HM-Exos were successfully isolated using the exosome extraction kit. The size and shape of HM-Exos were analyzed using DLS, SEM, and TEM. HM-Exos improved the migration potential of LPS-exposed HDPSCs. HM-Exos reduced the expression of inflammatory cytokines such as TNF-α, IL-1β, and IL-6 in LPS-exposed HDPSCs. |
| first_indexed | 2024-04-09T22:34:52Z |
| format | Article |
| id | doaj.art-5093bd95f45b49948097f987048c5938 |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-04-09T22:34:52Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-5093bd95f45b49948097f987048c59382023-03-22T12:34:17ZengBMCBMC Oral Health1472-68312023-02-012311910.1186/s12903-023-02796-4Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cellsEhsaneh Azaryan0Samira Karbasi1Mansoore Saharkhiz2Mohammad Yahya Hanafi-Bojd3Asghar Zarban4Fariba Emadian Razavi5Mohsen Naseri6Student Research Committee, Birjand University of Medical SciencesDepartment of Molecular Medicine, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical SciencesDepartment of Immunology, Faculty of Medicine, Birjand University of Medical SciencesCellular and Molecular Research Center, Birjand University of Medical SciencesCardiovascular Diseases Research Center, Birjand University of Medical SciencesDental Research Center, Faculty of Dentistry, Birjand University of Medical SciencesCellular and Molecular Research Center, Department of Molecular Medicine, Birjand University of Medical SciencesHighlights HM-Exos were successfully isolated using the exosome extraction kit. The size and shape of HM-Exos were analyzed using DLS, SEM, and TEM. HM-Exos improved the migration potential of LPS-exposed HDPSCs. HM-Exos reduced the expression of inflammatory cytokines such as TNF-α, IL-1β, and IL-6 in LPS-exposed HDPSCs.https://doi.org/10.1186/s12903-023-02796-4Dental pulp stem cellsExosomesInflammationLipopolysaccharide |
| spellingShingle | Ehsaneh Azaryan Samira Karbasi Mansoore Saharkhiz Mohammad Yahya Hanafi-Bojd Asghar Zarban Fariba Emadian Razavi Mohsen Naseri Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells BMC Oral Health Dental pulp stem cells Exosomes Inflammation Lipopolysaccharide |
| title | Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells |
| title_full | Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells |
| title_fullStr | Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells |
| title_full_unstemmed | Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells |
| title_short | Effect of HM-Exos on the migration and inflammatory response of LPS-exposed dental pulp stem cells |
| title_sort | effect of hm exos on the migration and inflammatory response of lps exposed dental pulp stem cells |
| topic | Dental pulp stem cells Exosomes Inflammation Lipopolysaccharide |
| url | https://doi.org/10.1186/s12903-023-02796-4 |
| work_keys_str_mv | AT ehsanehazaryan effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells AT samirakarbasi effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells AT mansooresaharkhiz effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells AT mohammadyahyahanafibojd effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells AT asgharzarban effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells AT faribaemadianrazavi effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells AT mohsennaseri effectofhmexosonthemigrationandinflammatoryresponseoflpsexposeddentalpulpstemcells |