Selective Antitumor Activity of Datelliptium toward Medullary Thyroid Carcinoma by Downregulating RET Transcriptional Activity

Selective Antitumor Activity of Datelliptium toward Medullary Thyroid Carcinoma by Downregulating RET Transcriptional Activity

Medullary thyroid carcinoma (MTC) is a rare aggressive form of thyroid cancer with high rates of metastasis. Sporadic and hereditary MTC are strongly driven by somatic and germline mutations, respectively, in the transmembrane REarranged during Transfection (RET) proto-oncogene, which encodes a rece...

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Bibliographic Details
Main Authors: Tariq Alqahtani, Abdullah Alswied, Daekyu Sun
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
RET
datelliptium
NSC311152
medullary thyroid carcinoma
Online Access:https://www.mdpi.com/2072-6694/13/13/3288

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