Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study
Introduction: Total Thyroidectomy (TT) is a standard surgical procedure for Multinodular Goiter (MNG). Transient hypocalcaemia is a frequent complication of TT with significant postoperative morbidity and long-term consequences. Many patient and surgical factors are attributed to postoperative...
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JCDR Research and Publications Pvt. Ltd.
2021-01-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
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| Online Access: | http://www.ijars.net/articles/PDF/2590/45888_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdf |
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| author | Bhavuray Teli R Santhosh MP Udayaravi PP Dinesh Satish Arkeri N Naveen Ganesan Karthick PR Venugopal |
| author_facet | Bhavuray Teli R Santhosh MP Udayaravi PP Dinesh Satish Arkeri N Naveen Ganesan Karthick PR Venugopal |
| author_sort | Bhavuray Teli |
| collection | DOAJ |
| description | Introduction: Total Thyroidectomy (TT) is a standard
surgical procedure for Multinodular Goiter (MNG). Transient
hypocalcaemia is a frequent complication of TT with significant
postoperative morbidity and long-term consequences. Many
patient and surgical factors are attributed to postoperative
hypocalcaemia. Vitamin D deficiency is one of the contributory
factors in few of the studies, which is a modifiable risk factor.
However, there is limited data to support the same.
Aim: To evaluate the effect of preoperative vitamin D deficiency on
postoperative hypocalcaemia in patients undergoing TT surgery.
Materials and Methods: This was a retrospective crosssectional, descriptive study done on patients undergoing TT for
MNG in a single general surgical unit at a tertiary care teaching
hospital in Southern India. The data pertaining to patients
undergoing TT for MNG between January 2017 to February 2018
were collected. Patients who had low preoperative vitamin D
levels before surgery were included. The preoperative vitamin D
levels were correlated with postsurgery total serum calcium
using pearson correlation and the association of preoperative
serum total calcium was examined with postoperative serum
total calcium by using paired t-test. The results were analysed
using Statistical Package for the Social Sciences (SPSS) Version
20. The p-value<0.05 was considered statistically significant.
Results: Thirty-two patients had preoperative documented
vitamin D deficiency. Preoperative mean serum vitamin D level
was 15.42 ng/mL (R=3.21 to 29 ng/mL). Mean preoperative
calcium level was 9.28±0.51 mg/dL at admission. Postoperatively
mean serum total calcium level was 8.54±0.47 mg/dL. There
was no correlation between preoperative vitamin D levels and
postoperative low serum calcium levels (Pearson R=0.154).
Conclusion: There was no influence of preoperative vitamin D
levels on postoperative transient hypocalcaemia. Prospective
studies with well-defined controls in a larger cohort are
needed for ascertaining the same, as it has wider clinical
implications. |
| first_indexed | 2024-12-15T00:36:55Z |
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| issn | 2277-8543 2455-6874 |
| language | English |
| last_indexed | 2024-12-15T00:36:55Z |
| publishDate | 2021-01-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
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| series | International Journal of Anatomy Radiology and Surgery |
| spelling | doaj.art-5095eb8b1bb6462eabd3fbbf83f863032022-12-21T22:41:46ZengJCDR Research and Publications Pvt. Ltd.International Journal of Anatomy Radiology and Surgery2277-85432455-68742021-01-01101SO05SO0810.7860/IJARS/2021/45888:2590Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional StudyBhavuray Teli0 R Santhosh1MP Udayaravi2 PP Dinesh3Satish Arkeri4N Naveen5Ganesan Karthick6PR Venugopal7Associate Professor, Department of Surgery, SN Medical College, Bagalkot, Karnataka, India.Assistant Professor, Department of Surgery, Malabar Medical College, Kozhikode, Kerala, India.Associate Professor, Department of Surgery, Malabar Medical College, Kozhikode, Kerala, India.Assistant Professor, Department of Surgery, Malabar Medical College, Kozhikode, Kerala, India.Assistant Professor, Department of Surgery, DM Wayanad Medical College, Kozhikode, Kerala, India.Senior Resident, Department of Surgery, Malabar Medical College, Kozhikode, Kerala, India.Senior Resident, Department of Surgery, DM Wayanad Medical College, Kozhikode, Kerala, India.Professor, Department of Surgery, DM Wayanad Medical College, Kozhikode, Kerala, India.Introduction: Total Thyroidectomy (TT) is a standard surgical procedure for Multinodular Goiter (MNG). Transient hypocalcaemia is a frequent complication of TT with significant postoperative morbidity and long-term consequences. Many patient and surgical factors are attributed to postoperative hypocalcaemia. Vitamin D deficiency is one of the contributory factors in few of the studies, which is a modifiable risk factor. However, there is limited data to support the same. Aim: To evaluate the effect of preoperative vitamin D deficiency on postoperative hypocalcaemia in patients undergoing TT surgery. Materials and Methods: This was a retrospective crosssectional, descriptive study done on patients undergoing TT for MNG in a single general surgical unit at a tertiary care teaching hospital in Southern India. The data pertaining to patients undergoing TT for MNG between January 2017 to February 2018 were collected. Patients who had low preoperative vitamin D levels before surgery were included. The preoperative vitamin D levels were correlated with postsurgery total serum calcium using pearson correlation and the association of preoperative serum total calcium was examined with postoperative serum total calcium by using paired t-test. The results were analysed using Statistical Package for the Social Sciences (SPSS) Version 20. The p-value<0.05 was considered statistically significant. Results: Thirty-two patients had preoperative documented vitamin D deficiency. Preoperative mean serum vitamin D level was 15.42 ng/mL (R=3.21 to 29 ng/mL). Mean preoperative calcium level was 9.28±0.51 mg/dL at admission. Postoperatively mean serum total calcium level was 8.54±0.47 mg/dL. There was no correlation between preoperative vitamin D levels and postoperative low serum calcium levels (Pearson R=0.154). Conclusion: There was no influence of preoperative vitamin D levels on postoperative transient hypocalcaemia. Prospective studies with well-defined controls in a larger cohort are needed for ascertaining the same, as it has wider clinical implications.http://www.ijars.net/articles/PDF/2590/45888_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdflow vitamin dmultinodular goiterpostoperative hypocalcaemia |
| spellingShingle | Bhavuray Teli R Santhosh MP Udayaravi PP Dinesh Satish Arkeri N Naveen Ganesan Karthick PR Venugopal Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study International Journal of Anatomy Radiology and Surgery low vitamin d multinodular goiter postoperative hypocalcaemia |
| title | Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study |
| title_full | Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study |
| title_fullStr | Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study |
| title_full_unstemmed | Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study |
| title_short | Effect of Preoperative Hypovitaminosis D on Post-Total Thyroidectomy Transient Hypocalcaemia: A Retrospective Cross-sectional Study |
| title_sort | effect of preoperative hypovitaminosis d on post total thyroidectomy transient hypocalcaemia a retrospective cross sectional study |
| topic | low vitamin d multinodular goiter postoperative hypocalcaemia |
| url | http://www.ijars.net/articles/PDF/2590/45888_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdf |
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