Antiproliferative Activity of Some Newly Synthesized Substituted Nicotinamides Candidates Using Pyridine-2(1H) thione Derivatives as Synthon

Antiproliferative Activity of Some Newly Synthesized Substituted Nicotinamides Candidates Using Pyridine-2(1H) thione Derivatives as Synthon

Bibliographic Details
Main Authors:	Dina H. Elnaggar, Ashraf M. Mohamed, Naglaa A. Abdel Hafez, Mohamed E. Azab, Manar E. A. Elasasy, Hanem M. Awad, Thoraya A. Farghaly, Abd El-Galil E. Amr
Format:	Article
Language:	English
Published:	American Chemical Society 2022-03-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.1c06951

Similar Items

Antiproliferative Activity of Some Newly Synthesized Substituted Pyridine Candidates Using 4‑(Aaryl)-6-(naphthalen-1-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile as Synthon
by: Amira A. El-Sayed, et al.
Published: (2021-03-01)

Synthesis, Antiproliferative, and Antioxidant Evaluation of 2-Pentylquinazolin-4(3<i>H</i>)-one(thione) Derivatives with DFT Study
by: Amira A. El-Sayed, et al.
Published: (2019-10-01)

Reactions of hydrazonoyl halides with heterocyclic thiones. Convenient methodology for heteroannulation, synthesis of spiroheterocycles and heterocyclic ring transformation
by: Ahmad Sami Shawali, et al.
Published: (2008-02-01)

Multicomponent Solids of Niflumic and Mefenamic Acids Based on Acid-Pyridine Synthon
by: Vineet Kumar, et al.
Published: (2022-03-01)

Synthesis of Chiral Macrocyclic or Linear Pyridine Carboxamides from Pyridine-2,6-dicarbonyl Dichloride as Antimicrobial Agents
by: Abd El-Galil E Amr, et al.
Published: (2010-09-01)

Synthesis of Some New Pyridine-2,6-carboxamide-derived Schiff Bases as Potential Antimicrobial Agents
by: Abd El-Galil E. Amr, et al.
Published: (2010-07-01)

2-Methylsulfanyl-1,2,4-triazolo[1,5-a]quinazoline-5(4H)-thione
by: Seik Weng Ng, et al.
Published: (2013-03-01)

Synthesis of Chitosan-La<sub>2</sub>O<sub>3</sub> Nanocomposite and Its Utility as a Powerful Catalyst in the Synthesis of Pyridines and Pyrazoles
by: Khaled D. Khalil, et al.
Published: (2021-06-01)

catena-Poly[μ2-iodido-diiodidobis(μ3-pyridine-2-thione-κ3S:S:S)(μ2-pyridine-2-thione-κ2S:S)tricopper(I)]
by: Fang Ke, et al.
Published: (2013-02-01)

Dicarboxylic Acid-Based Co-Crystals of Pyridine Derivatives Involving Structure Guiding Unconventional Synthons: Experimental and Theoretical Studies
by: Pranay Sharma, et al.
Published: (2022-10-01)

Fluorination Homologation of Biorenewable Synthon Cyrene
by: Johannes Puschnig, et al.
Published: (2024-12-01)

Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
by: Mohamed E. Azab, et al.
Published: (2015-10-01)

New titanium imido synthons: syntheses and supramolecular structures.
by: Adams, N, et al.
Published: (2005)

Synthesis and antiproliferative activity studies of new functionalized pyridine linked thiazole derivatives
by: Alaa M. Alqahtani, et al.
Published: (2021-01-01)

Assessment of Computational Tools for Predicting Supramolecular Synthons
by: Bhupinder Sandhu, et al.
Published: (2021-05-01)

Tetramethylphosphinane as a new secondary phosphine synthon
by: James D. Nobbs, et al.
Published: (2023-04-01)

Supramolecular Synthon Identification in Azelaic Acid – Isonicotinamide
by: Jayasubba Reddy Yarava, et al.
Published: (2022-06-01)

Effects of nanoparticles with hydrotropic nicotinamide on tacrolimus: permeability through psoriatic skin and antipsoriatic and antiproliferative activities
by: Wan T, et al.
Published: (2017-02-01)

Gold(III) Pyridine-Benzimidazole Complexes as Aquaglyceroporin Inhibitors and Antiproliferative Agents
by: Brech Aikman, et al.
Published: (2018-11-01)

Design, Synthesis, and Antiproliferative Activity of Novel Neocryptolepine–Rhodanine Hybrids
by: Mohamed El-Bahnsawye, et al.
Published: (2022-11-01)

Azomethine Ylides—Versatile Synthons for Pyrrolidinyl-Heterocyclic Compounds
by: Siva S. Panda, et al.
Published: (2023-01-01)

Acyl anion synthons: benzotriazole stabilized compared to classical
by: Alan R. Katritzky, et al.
Published: (2006-04-01)

Preparation of trinucleotide phosphoramidites as synthons for the synthesis of gene libraries
by: Ruth Suchsland, et al.
Published: (2018-02-01)

Crystal structure of 1,4-dihydro-1-phenylchromeno[4,3-c]pyrazole, C16H12N2O
by: Amr Abd El-Galil E., et al.
Published: (2016-12-01)

Antiproliferative and Antiangiogenic Properties of New VEGFR-2-targeting 2-thioxobenzo[<i>g</i>]quinazoline Derivatives (In Vitro)
by: Hatem A. Abuelizz, et al.
Published: (2020-12-01)

Design, ecofriendly synthesis, anticancer and antimicrobial screening of innovative Biginelli dihydropyrimidines using β-aroylpyruvates as synthons
by: Afaf El-Malah, et al.
Published: (2021-04-01)

1-Phenylpyrazolo[4',3':5,6]pyrano[3,2-c]pyridine-4(1H)-thione
by: Wolfgang Holzer, et al.
Published: (2010-04-01)

H-ferrierite zeolite: As an effective and reusable heterogeneous catalyst for synthesis of 1,5-benzothiazepine under solvent free condition and 1,3-dipolar cycloaddition in water
by: Thoraya A. Farghaly, et al.
Published: (2017-05-01)

Novel Catalyst-Free Synthesis of Some 3‑Alkylaminoquinoxaline-2(1H)‑thiones and 3‑Alkyloxyquinoxaline-2(1H)‑thiones in Ethanol
by: Samir M. El Rayes, et al.
Published: (2025-01-01)

Designing organic syntheses : a programmed introduction to the synthon approach/
by: 223643 Warren, Stuart
Published: (1978)

Supramolecular Frameworks Based on Rhenium Clusters Using the Synthons Approach
by: Nathalie Audebrand, et al.
Published: (2021-05-01)

Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds
by: Shabber Mohammed, et al.
Published: (2022-05-01)

Pb center dot center dot center dot pi aryl interactions as supramolecular synthons
by: Tiekink, E.R.T., et al.
Published: (2010)

Pyrimidyl formamidine palladium(II) complex as a nanocatalyst for aqueous Suzuki-Miyaura coupling
by: Afaf Y. Khormi, et al.
Published: (2019-03-01)

Novel Antiproliferative Biphenyl Nicotinamide: NMR Metabolomic Study of its Effect on the MCF-7 Cell in Comparison with Cisplatin and Vinblastine
by: Laura Del Coco, et al.
Published: (2020-07-01)

2(3H)-Furanones as synthons for polyamides of 1,3-diazines and 1,3,5-triazines
by: Abdel-Sattar S. Hamad Elgazwy, et al.
Published: (2006-04-01)

Crystal structure of 4-phenyl-5-(pyridin-2-yl)-1-((pyridin-2-yl)methyl)- 1H-imidazole-2(3H)-thione, C20H16N4S
by: Mukiza Janvier, et al.
Published: (2014-12-01)

Synthesis and Characterization of Macrocyclic Chiral Tröger’s Base Phenhomazine Candidates as Anticancer Agent
by: Alhussein A. Ibrahim, et al.
Published: (2021-01-01)

Integrating and Exploiting Molecular, Supramolecular, and Time Crystal Synthons in Advanced Synthesis
by: Indrajit Chakraborty, et al.
Published: (2024-10-01)

Dihydroxyacetone: A User Guide for a Challenging Bio-Based Synthon
by: Léo Bricotte, et al.
Published: (2023-03-01)