Functional polarization of tumor-associated macrophages dictated by metabolic reprogramming

Functional polarization of tumor-associated macrophages dictated by metabolic reprogramming

Abstract Macrophages are highly plastic in different tissues and can differentiate into functional subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of the most important innate immune cells implicated in the establishment of an immunosuppressive tumor microenvironm...

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Bibliographic Details
Main Authors: Wentao Zeng, Fei Li, Shikai Jin, Ping-Chih Ho, Pu-Ste Liu, Xin Xie
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TAMs
TME
Metabolic reprogramming
Polarization
Signaling pathways
Online Access:https://doi.org/10.1186/s13046-023-02832-9

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