CD4+ T cells are required to improve the efficacy of CIK therapy in non-small cell lung cancer
Herein, Liu and colleagues show that CD4+ T cells in cytokine-induced killer (CIK) cells are required to enhance the clinical efficacy of CIK therapy. In addition, CD4+ T cells help via IL-17A production is critical to restoring the function of CD8+/CD3+CD56+ T cells and reversing the exhaustion of...
Full description
Bibliographic Details
| Main Authors: |
Shaochuan Liu,
Yuan Meng,
Liang Liu,
Yingge Lv,
Wenwen Yu,
Ting Liu,
Limei Wang,
Di Mu,
Qiuru Zhou,
Min Liu,
Yulin Ren,
Dong Zhang,
Baihui Li,
Qian Sun,
Xiubao Ren |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2022-05-01
|
|---|
| Series: | Cell Death and Disease
|
|---|
| Online Access: | https://doi.org/10.1038/s41419-022-04882-x
|
|---|