Interplay between bladder microbiota and urinary antimicrobial peptides: mechanisms for human urinary tract infection risk and symptom severity.

Interplay between bladder microbiota and urinary antimicrobial peptides: mechanisms for human urinary tract infection risk and symptom severity.

Resident bacterial communities (microbiota) and host antimicrobial peptides (AMPs) are both essential components of normal host innate immune responses that limit infection and pathogen induced inflammation. However, their interdependence has not been investigated in the context of urinary tract inf...

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Main Authors: Vanessa Nienhouse, Xiang Gao, Qunfeng Dong, David E Nelson, Evelyn Toh, Kathleen McKinley, Paul Schreckenberger, Noriko Shibata, Cynthia S Fok, Elizabeth R Mueller, Linda Brubaker, Alan J Wolfe, Katherine A Radek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259481?pdf=render

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