COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports
Abstract Aims To summarize published case reports of patients diagnosed with coronavirus disease 2019 (COVID‐19) and Brugada pattern electrocardiogram (ECG). Methods The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses checklist were followed. A literature search was conducted usin...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-05-01
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| Series: | Annals of Noninvasive Electrocardiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/anec.13051 |
| _version_ | 1797823763830538240 |
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| author | Kevin Liu Kai Chen Ekin C. Uzunoglu Azeem Rathore Tanya Deol Ele Wu Claude S. Elayi Prakash G. Suryanarayana Stephen G. Keim John N. Catanzaro |
| author_facet | Kevin Liu Kai Chen Ekin C. Uzunoglu Azeem Rathore Tanya Deol Ele Wu Claude S. Elayi Prakash G. Suryanarayana Stephen G. Keim John N. Catanzaro |
| author_sort | Kevin Liu |
| collection | DOAJ |
| description | Abstract Aims To summarize published case reports of patients diagnosed with coronavirus disease 2019 (COVID‐19) and Brugada pattern electrocardiogram (ECG). Methods The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses checklist were followed. A literature search was conducted using PubMed, EMBASE, and Scopus up until September 2021. The incidence, clinical characteristics, and management outcomes of COVID‐19 patients with a Brugada pattern ECG were identified. Results A total of 18 cases were collected. The mean age was 47.1 years and 11.1% were women. No patients had prior confirmed diagnosis of Brugada syndrome. The most common presenting clinical symptoms were fever (83.3%), chest pain (38.8%), shortness of breath (38.8%), and syncope (16.6%). All 18 patients presented with type 1 Brugada pattern ECG. Four patients (22.2%) underwent left heart catheterization, and none demonstrated the presence of obstructive coronary disease. The most common reported therapies included antipyretics (55.5%), hydroxychloroquine (27.7%), and antibiotics (16.6%). One patient (5.5%) died during hospitalization. Three patients (16.6%) who presented with syncope received either an implantable cardioverter defibrillator or wearable cardioverter defibrillator at discharge. At follow‐up, 13 patients (72.2%) had resolution of type 1 Brugada pattern ECG. Conclusion COVID‐19‐associated Brugada pattern ECG seems relatively rare. Most patients had resolution of the ECG pattern once their symptoms have improved. Increased awareness and timely use of antipyretics is warranted in this population. |
| first_indexed | 2024-03-13T10:28:46Z |
| format | Article |
| id | doaj.art-50a2c853d3e740449f49a23ee72bb7aa |
| institution | Directory Open Access Journal |
| issn | 1082-720X 1542-474X |
| language | English |
| last_indexed | 2024-03-13T10:28:46Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Noninvasive Electrocardiology |
| spelling | doaj.art-50a2c853d3e740449f49a23ee72bb7aa2023-05-19T03:57:51ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2023-05-01283n/an/a10.1111/anec.13051COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reportsKevin Liu0Kai Chen1Ekin C. Uzunoglu2Azeem Rathore3Tanya Deol4Ele Wu5Claude S. Elayi6Prakash G. Suryanarayana7Stephen G. Keim8John N. Catanzaro9Department of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USACHI Saint Joseph Hospital – Cardiology Lexington Kentucky USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USADepartment of Medicine, Division of Cardiology, Section of Electrophysiology University of Florida Health Science Center Florida Jacksonville USAAbstract Aims To summarize published case reports of patients diagnosed with coronavirus disease 2019 (COVID‐19) and Brugada pattern electrocardiogram (ECG). Methods The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses checklist were followed. A literature search was conducted using PubMed, EMBASE, and Scopus up until September 2021. The incidence, clinical characteristics, and management outcomes of COVID‐19 patients with a Brugada pattern ECG were identified. Results A total of 18 cases were collected. The mean age was 47.1 years and 11.1% were women. No patients had prior confirmed diagnosis of Brugada syndrome. The most common presenting clinical symptoms were fever (83.3%), chest pain (38.8%), shortness of breath (38.8%), and syncope (16.6%). All 18 patients presented with type 1 Brugada pattern ECG. Four patients (22.2%) underwent left heart catheterization, and none demonstrated the presence of obstructive coronary disease. The most common reported therapies included antipyretics (55.5%), hydroxychloroquine (27.7%), and antibiotics (16.6%). One patient (5.5%) died during hospitalization. Three patients (16.6%) who presented with syncope received either an implantable cardioverter defibrillator or wearable cardioverter defibrillator at discharge. At follow‐up, 13 patients (72.2%) had resolution of type 1 Brugada pattern ECG. Conclusion COVID‐19‐associated Brugada pattern ECG seems relatively rare. Most patients had resolution of the ECG pattern once their symptoms have improved. Increased awareness and timely use of antipyretics is warranted in this population.https://doi.org/10.1111/anec.13051BrugadaCOVIDelectrocardiogram |
| spellingShingle | Kevin Liu Kai Chen Ekin C. Uzunoglu Azeem Rathore Tanya Deol Ele Wu Claude S. Elayi Prakash G. Suryanarayana Stephen G. Keim John N. Catanzaro COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports Annals of Noninvasive Electrocardiology Brugada COVID electrocardiogram |
| title | COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports |
| title_full | COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports |
| title_fullStr | COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports |
| title_full_unstemmed | COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports |
| title_short | COVID‐19‐associated Brugada pattern electrocardiogram: Systematic review of case reports |
| title_sort | covid 19 associated brugada pattern electrocardiogram systematic review of case reports |
| topic | Brugada COVID electrocardiogram |
| url | https://doi.org/10.1111/anec.13051 |
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