Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia
In shift work settings and on-call operations, workers may be at risk of sleep inertia when called to action immediately after awakening from sleep. However, individuals may differ substantially in their susceptibility to sleep inertia. We investigated this using data from a laboratory study in whic...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Clocks & Sleep |
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| Online Access: | https://www.mdpi.com/2624-5175/3/2/19 |
| _version_ | 1797531576854118400 |
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| author | Kirsie R. Lundholm Kimberly A. Honn Lillian Skeiky Rachael A. Muck Hans P. A. Van Dongen |
| author_facet | Kirsie R. Lundholm Kimberly A. Honn Lillian Skeiky Rachael A. Muck Hans P. A. Van Dongen |
| author_sort | Kirsie R. Lundholm |
| collection | DOAJ |
| description | In shift work settings and on-call operations, workers may be at risk of sleep inertia when called to action immediately after awakening from sleep. However, individuals may differ substantially in their susceptibility to sleep inertia. We investigated this using data from a laboratory study in which 20 healthy young adults were each exposed to 36 h of total sleep deprivation, preceded by a baseline sleep period and followed by a recovery sleep period, on three separate occasions. In the week prior to each laboratory session and on the corresponding baseline night in the laboratory, participants either extended their sleep period to 12 h/day or restricted it to 6 h/day. During periods of wakefulness in the laboratory, starting right after scheduled awakening, participants completed neurobehavioral tests every 2 h. Testing included the Karolinska Sleepiness Scale to measure subjective sleepiness, for which the data were analyzed with nonlinear mixed-effects regression to quantify sleep inertia. This revealed considerable interindividual differences in the magnitude of sleep inertia, which were highly stable within individuals after both baseline and recovery sleep periods, regardless of study condition. Our results demonstrate that interindividual differences in subjective sleepiness due to sleep inertia are substantial and constitute a trait. |
| first_indexed | 2024-03-10T10:45:47Z |
| format | Article |
| id | doaj.art-50a42a3ebf3b4ef5bc8f0759e17170c4 |
| institution | Directory Open Access Journal |
| issn | 2624-5175 |
| language | English |
| last_indexed | 2024-03-10T10:45:47Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Clocks & Sleep |
| spelling | doaj.art-50a42a3ebf3b4ef5bc8f0759e17170c42023-11-21T22:36:58ZengMDPI AGClocks & Sleep2624-51752021-06-013229831110.3390/clockssleep3020019Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep InertiaKirsie R. Lundholm0Kimberly A. Honn1Lillian Skeiky2Rachael A. Muck3Hans P. A. Van Dongen4Sleep and Performance Research Center & Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USASleep and Performance Research Center & Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USASleep and Performance Research Center & Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USASleep and Performance Research Center & Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USASleep and Performance Research Center & Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USAIn shift work settings and on-call operations, workers may be at risk of sleep inertia when called to action immediately after awakening from sleep. However, individuals may differ substantially in their susceptibility to sleep inertia. We investigated this using data from a laboratory study in which 20 healthy young adults were each exposed to 36 h of total sleep deprivation, preceded by a baseline sleep period and followed by a recovery sleep period, on three separate occasions. In the week prior to each laboratory session and on the corresponding baseline night in the laboratory, participants either extended their sleep period to 12 h/day or restricted it to 6 h/day. During periods of wakefulness in the laboratory, starting right after scheduled awakening, participants completed neurobehavioral tests every 2 h. Testing included the Karolinska Sleepiness Scale to measure subjective sleepiness, for which the data were analyzed with nonlinear mixed-effects regression to quantify sleep inertia. This revealed considerable interindividual differences in the magnitude of sleep inertia, which were highly stable within individuals after both baseline and recovery sleep periods, regardless of study condition. Our results demonstrate that interindividual differences in subjective sleepiness due to sleep inertia are substantial and constitute a trait.https://www.mdpi.com/2624-5175/3/2/19human phenotypeintraclass correlation coefficientKarolinska Sleepiness Scalenonlinear mixed-effects modelingon-call workrecovery sleep |
| spellingShingle | Kirsie R. Lundholm Kimberly A. Honn Lillian Skeiky Rachael A. Muck Hans P. A. Van Dongen Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia Clocks & Sleep human phenotype intraclass correlation coefficient Karolinska Sleepiness Scale nonlinear mixed-effects modeling on-call work recovery sleep |
| title | Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia |
| title_full | Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia |
| title_fullStr | Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia |
| title_full_unstemmed | Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia |
| title_short | Trait Interindividual Differences in the Magnitude of Subjective Sleepiness from Sleep Inertia |
| title_sort | trait interindividual differences in the magnitude of subjective sleepiness from sleep inertia |
| topic | human phenotype intraclass correlation coefficient Karolinska Sleepiness Scale nonlinear mixed-effects modeling on-call work recovery sleep |
| url | https://www.mdpi.com/2624-5175/3/2/19 |
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