A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults

This cohort study investigated the impact of chronic diseases on fall risk in middle-aged and older individuals, offering insights for fall prevention strategies. Analysing data from 4,670 participants aged 40+ years, we used a Cox proportional risk model to assess chronic disease types, numbers, an...

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Main Authors: Yang Xue, Li Longxin, Xie Fang, Wang Zhang
Format: Article
Language:English
Published: De Gruyter 2023-07-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0748
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author Yang Xue
Li Longxin
Xie Fang
Wang Zhang
author_facet Yang Xue
Li Longxin
Xie Fang
Wang Zhang
author_sort Yang Xue
collection DOAJ
description This cohort study investigated the impact of chronic diseases on fall risk in middle-aged and older individuals, offering insights for fall prevention strategies. Analysing data from 4,670 participants aged 40+ years, we used a Cox proportional risk model to assess chronic disease types, numbers, and interactions with other factors on fall injury risk across age groups. Results showed that middle-aged adults with respiratory diseases had a 26% increased fall risk (hazard ratio [HR] = 1.26, 95% confidence interval [CI]: 1.05–1.48), and a linear dose–response relationship was observed between chronic disease number and fall risk (p < 0.001). The study also examined interaction effects of chronic diseases with gender, disability, and fall injury history. Female middle-aged and older adults with chronic diseases had a 67% higher fall risk than their male counterparts without chronic diseases (HR = 1.67, 95% CI: 1.36–1.88). In conclusion, chronically ill middle-aged and older adults have a higher fall risk, with high-risk groups including women, those with chronic diseases, and individuals with fall injury history. Fall prevention efforts should target middle-aged adults as well.
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spelling doaj.art-50a63947ecf644b5bbe4ba2f3155a1be2023-07-17T05:25:15ZengDe GruyterOpen Medicine2391-54632023-07-01181i31110.1515/med-2023-0748A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adultsYang Xue0Li Longxin1Xie Fang2Wang Zhang3Department of Geriatrics, The General Hospital of Western Theater Command, Chengdu, P.R. ChinaDepartment of Geriatrics, The General Hospital of Western Theater Command, Chengdu, P.R. ChinaDepartment of Geriatrics, The General Hospital of Western Theater Command, Chengdu, P.R. ChinaDepartment of Geriatrics, The General Hospital of Western Theater Command, Chengdu, P.R. ChinaThis cohort study investigated the impact of chronic diseases on fall risk in middle-aged and older individuals, offering insights for fall prevention strategies. Analysing data from 4,670 participants aged 40+ years, we used a Cox proportional risk model to assess chronic disease types, numbers, and interactions with other factors on fall injury risk across age groups. Results showed that middle-aged adults with respiratory diseases had a 26% increased fall risk (hazard ratio [HR] = 1.26, 95% confidence interval [CI]: 1.05–1.48), and a linear dose–response relationship was observed between chronic disease number and fall risk (p < 0.001). The study also examined interaction effects of chronic diseases with gender, disability, and fall injury history. Female middle-aged and older adults with chronic diseases had a 67% higher fall risk than their male counterparts without chronic diseases (HR = 1.67, 95% CI: 1.36–1.88). In conclusion, chronically ill middle-aged and older adults have a higher fall risk, with high-risk groups including women, those with chronic diseases, and individuals with fall injury history. Fall prevention efforts should target middle-aged adults as well.https://doi.org/10.1515/med-2023-0748chronic diseasefall injuryrisk factorshealth managementcohort studies
spellingShingle Yang Xue
Li Longxin
Xie Fang
Wang Zhang
A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults
Open Medicine
chronic disease
fall injury
risk factors
health management
cohort studies
title A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults
title_full A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults
title_fullStr A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults
title_full_unstemmed A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults
title_short A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults
title_sort prospective cohort study of the impact of chronic disease on fall injuries in middle aged and older adults
topic chronic disease
fall injury
risk factors
health management
cohort studies
url https://doi.org/10.1515/med-2023-0748
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