Design and evaluation of glutathione responsive glycosylated camptothecin nanosupramolecular prodrug

Design and evaluation of glutathione responsive glycosylated camptothecin nanosupramolecular prodrug

A novel tumor-targeted glutathione responsive Glycosylated-Camptothecin nanosupramolecular prodrug (CPT-GL NSp) was designed and fabricated via a disulfide bond. The effects of glycoligand with different polarities on solubility, self-assembly, stability, cellular uptake, and glutathione responsive...

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Bibliographic Details
Main Authors:	Wenhua Li, Zhong Chen, Xiaoying Liu, Mingming Lian, Haisheng Peng, Changmei Zhang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2021-01-01
Series:	Drug Delivery
Subjects:	glutathione camptothecin glycosylated nanosupramolecular prodrug anti-tumor ability
Online Access:	http://dx.doi.org/10.1080/10717544.2021.1977424

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