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author Lionel J. Clarke
author_facet Lionel J. Clarke
author_sort Lionel J. Clarke
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description Synthetic biology is transforming the ability to manufacture increasingly needed bio-based products in response to rising market demand. By applying engineering principles to the convolution of recent advances in genomic engineering techniques, information technology and automation, synthetic biology is facilitating the replacement of time-consuming ‘discover and grow’ approaches by more precise and affordable ‘biodesign and biomanufacture’ processes. Meantime, societal awareness of specific health, well-being, and environmental issues is increasing ‘market pull’ that will shape future pathways to commercialisation. Market interests will not only shape targets for product function and cost but also increasingly question their provenance. Sustainability concerns are already driving demand to replace petrochemical-derived by bio-derived products, but many established industries wishing to transition may lack familiarity with bio-manufacturing processes and with the wider issues associated with large-scale bio-feedstock supply chains. Meantime, commercialisation of synthetic biology today is being advanced mostly via start-ups and SMEs. Combining the knowledge and skills required to respond to market interests, as the scale of operations and complexity of issues expands, is likely to stimulate an increasing diversity of collaborative approaches.
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spelling doaj.art-50ab1b20c7fa44fc81ad457610b88b362022-12-21T23:12:35ZengWileyEngineering Biology2398-61822019-02-0110.1049/enb.2018.5009ENB.2018.5009Synthetic biology – pathways to commercialisationLionel J. Clarke0Imperial CollegeSynthetic biology is transforming the ability to manufacture increasingly needed bio-based products in response to rising market demand. By applying engineering principles to the convolution of recent advances in genomic engineering techniques, information technology and automation, synthetic biology is facilitating the replacement of time-consuming ‘discover and grow’ approaches by more precise and affordable ‘biodesign and biomanufacture’ processes. Meantime, societal awareness of specific health, well-being, and environmental issues is increasing ‘market pull’ that will shape future pathways to commercialisation. Market interests will not only shape targets for product function and cost but also increasingly question their provenance. Sustainability concerns are already driving demand to replace petrochemical-derived by bio-derived products, but many established industries wishing to transition may lack familiarity with bio-manufacturing processes and with the wider issues associated with large-scale bio-feedstock supply chains. Meantime, commercialisation of synthetic biology today is being advanced mostly via start-ups and SMEs. Combining the knowledge and skills required to respond to market interests, as the scale of operations and complexity of issues expands, is likely to stimulate an increasing diversity of collaborative approaches.https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5009genomicsbiofuelmanufacturing processesbioenergy conversionbiotechnologysupply chainscellular biophysicssustainable developmentpetrochemicalsindustrial economicssynthetic biology – pathwayscommercialisationauthorsbio-based productsrising market demandengineering principlesconvolutiongenomic engineering techniquestime-consumingaffordable biodesignbiomanufacture processessocietal awarenessspecific healthenvironmental issuesmarket pullfuture pathwaysmarket interestsproduct functioncostsustainability concernspetrochemical-derivedbio-derived productsbio-manufacturing processeswider issueslarge-scale bio-feedstock supply chainssynthetic biology todayissues expandsincreasing diversity
spellingShingle Lionel J. Clarke
Synthetic biology – pathways to commercialisation
Engineering Biology
genomics
biofuel
manufacturing processes
bioenergy conversion
biotechnology
supply chains
cellular biophysics
sustainable development
petrochemicals
industrial economics
synthetic biology – pathways
commercialisation
authors
bio-based products
rising market demand
engineering principles
convolution
genomic engineering techniques
time-consuming
affordable biodesign
biomanufacture processes
societal awareness
specific health
environmental issues
market pull
future pathways
market interests
product function
cost
sustainability concerns
petrochemical-derived
bio-derived products
bio-manufacturing processes
wider issues
large-scale bio-feedstock supply chains
synthetic biology today
issues expands
increasing diversity
title Synthetic biology – pathways to commercialisation
title_full Synthetic biology – pathways to commercialisation
title_fullStr Synthetic biology – pathways to commercialisation
title_full_unstemmed Synthetic biology – pathways to commercialisation
title_short Synthetic biology – pathways to commercialisation
title_sort synthetic biology pathways to commercialisation
topic genomics
biofuel
manufacturing processes
bioenergy conversion
biotechnology
supply chains
cellular biophysics
sustainable development
petrochemicals
industrial economics
synthetic biology – pathways
commercialisation
authors
bio-based products
rising market demand
engineering principles
convolution
genomic engineering techniques
time-consuming
affordable biodesign
biomanufacture processes
societal awareness
specific health
environmental issues
market pull
future pathways
market interests
product function
cost
sustainability concerns
petrochemical-derived
bio-derived products
bio-manufacturing processes
wider issues
large-scale bio-feedstock supply chains
synthetic biology today
issues expands
increasing diversity
url https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5009
work_keys_str_mv AT lioneljclarke syntheticbiologypathwaystocommercialisation