Periodontal disease does not increase the risk of subsequent psoriasis
Abstract Previous studies suggested that chronic periodontitis may be a risk factor for psoriasis. However, no study has confirmed this relationship for all stages of periodontal disease (gingivitis and periodontitis). This nationwide population-based retrospective cohort study aimed to investigate...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-32907-8 |
| _version_ | 1797845939923189760 |
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| author | Yoo Sang Baek Eun-Jung Kwak Young Chan Kim Ko Eun Kim Hae Jun Song Jiehyun Jeon |
| author_facet | Yoo Sang Baek Eun-Jung Kwak Young Chan Kim Ko Eun Kim Hae Jun Song Jiehyun Jeon |
| author_sort | Yoo Sang Baek |
| collection | DOAJ |
| description | Abstract Previous studies suggested that chronic periodontitis may be a risk factor for psoriasis. However, no study has confirmed this relationship for all stages of periodontal disease (gingivitis and periodontitis). This nationwide population-based retrospective cohort study aimed to investigate whether periodontal disease is an independent risk factor for the development of subsequent psoriasis. Patients aged ≥ 20 years who underwent both medical and oral checkups from the National Health Screening Program between 2002 and 2007 were selected from a customized database provided by the National Health Insurance Service (NHIS). Then, patients with periodontal disease (n = 3,682,468) and without periodontal disease (control, n = 3,637,128) according to oral examination results were identified. We tracked each patient for subsequent psoriasis diagnosis until the end of 2018 using NHIS database. The incidence rates of psoriasis per 1000 person-years were 0.36 and 0.34 in the periodontal disease group and control groups, respectively. After adjusting for potential cofactors, no significant increase in risk (adjusted hazard ratio, 0.994; 95% confidence interval, 0.974–1.015) was observed. Similar results were observed when analyzing the risk of psoriasis in patients who required scaling or periodontal surgery. In conclusion, periodontal disease is not an independent risk factor of psoriasis. |
| first_indexed | 2024-04-09T17:47:02Z |
| format | Article |
| id | doaj.art-50ac94f96bdb43b0a7a149186f9137b1 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T17:47:02Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-50ac94f96bdb43b0a7a149186f9137b12023-04-16T11:14:49ZengNature PortfolioScientific Reports2045-23222023-04-011311710.1038/s41598-023-32907-8Periodontal disease does not increase the risk of subsequent psoriasisYoo Sang Baek0Eun-Jung Kwak1Young Chan Kim2Ko Eun Kim3Hae Jun Song4Jiehyun Jeon5Department of Dermatology, Guro Hospital, Korea University College of MedicineNational Dental Care Center for Person with Special Needs, Seoul National University Dental HospitalDepartment of Dermatology, Guro Hospital, Korea University College of MedicineDepartment of Dermatology, Guro Hospital, Korea University College of MedicineDepartment of Dermatology, Guro Hospital, Korea University College of MedicineDepartment of Dermatology, Guro Hospital, Korea University College of MedicineAbstract Previous studies suggested that chronic periodontitis may be a risk factor for psoriasis. However, no study has confirmed this relationship for all stages of periodontal disease (gingivitis and periodontitis). This nationwide population-based retrospective cohort study aimed to investigate whether periodontal disease is an independent risk factor for the development of subsequent psoriasis. Patients aged ≥ 20 years who underwent both medical and oral checkups from the National Health Screening Program between 2002 and 2007 were selected from a customized database provided by the National Health Insurance Service (NHIS). Then, patients with periodontal disease (n = 3,682,468) and without periodontal disease (control, n = 3,637,128) according to oral examination results were identified. We tracked each patient for subsequent psoriasis diagnosis until the end of 2018 using NHIS database. The incidence rates of psoriasis per 1000 person-years were 0.36 and 0.34 in the periodontal disease group and control groups, respectively. After adjusting for potential cofactors, no significant increase in risk (adjusted hazard ratio, 0.994; 95% confidence interval, 0.974–1.015) was observed. Similar results were observed when analyzing the risk of psoriasis in patients who required scaling or periodontal surgery. In conclusion, periodontal disease is not an independent risk factor of psoriasis.https://doi.org/10.1038/s41598-023-32907-8 |
| spellingShingle | Yoo Sang Baek Eun-Jung Kwak Young Chan Kim Ko Eun Kim Hae Jun Song Jiehyun Jeon Periodontal disease does not increase the risk of subsequent psoriasis Scientific Reports |
| title | Periodontal disease does not increase the risk of subsequent psoriasis |
| title_full | Periodontal disease does not increase the risk of subsequent psoriasis |
| title_fullStr | Periodontal disease does not increase the risk of subsequent psoriasis |
| title_full_unstemmed | Periodontal disease does not increase the risk of subsequent psoriasis |
| title_short | Periodontal disease does not increase the risk of subsequent psoriasis |
| title_sort | periodontal disease does not increase the risk of subsequent psoriasis |
| url | https://doi.org/10.1038/s41598-023-32907-8 |
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