| Summary: | Abdirahman Mohamed Hassan Dirie,1 Sedat Çolakoğlu,1 Osman Muhyadin Abdulle,2 Bashir Mohamud Abdi,3 Mohamed Abdi Osman,4 Abdiaziz Mohamud Shire,5 Abdinafic Mohamud Hussein6 1Pulmonology Department, Somalia Mogadishu Turkey Recep Tayyip Erdogan Training and Research Hospital, Mogadishu, Banadir, Somalia; 2Manager of the Multi-Drug Resistant Center in Southern Somalia, Mogadishu, Banadir, Somalia; 3HIV Program manager, Ministry of Health, Somali Federal Government, Mogadishu, Banadir, Somalia; 4Infectious and Microbiology Department, Somalia Mogadishu Turkey Recep Tayyip Erdogan Training and Research Hospital, Mogadishu, Banadir, Somalia; 5National TB program Manager, Somali Federal Government, Ministry of Health, Mogadishu, Banadir, Somalia; 6Cardiovascular Surgery Department, Somalia Mogadishu Turkey Recep Tayyip Erdogan Training and Research Hospital, Mogadishu, Banadir, SomaliaCorrespondence: Abdirahman Mohamed Hassan Dirie, Tel +252615479778, Email dirie515@gmail.comBackground: Tuberculosis (TB) is an infectious disease that is the second most common cause of death from a single infectious agent. TB infection affects anyone, regardless of age, gender, and ethnicity. Drug-resistant TB is a serious public health problem, which needs treatment with a second-line anti-TB drug and it includes poly-drug resistance (PDR), multi-drug resistance (MDR), and extensive drug resistance (XDR). The goal of this research is to find out the prevalence of MDR TB among pulmonary TB patients in Banadir, Somalia.Methods: This was a multicenter retrospective review of data involving 1732 smear-positive pulmonary TB patients visiting Banadir TB centers between July 1, 2019 and June 30, 2020. Demographic, clinical, and drug susceptibility data were retrieved from TB treatment cards. The data were analyzed using Statistical Package for Social Sciences (SPSS) software (IBM SPSS Statistics version 26).Results: All 1732 pulmonary TB cases were previously diagnosed by the Gene Xpert MTB/RIF test. Among them, 70.4% (1219/1732) were males. The mean age was 31.77 years. Overall, the prevalence of drug resistance TB was 10.56% (183/1732). The MDR TB was 1.96%, poly-drug resistance (PDR) was 0.12%, and extensive drug resistance was 0.06%.Conclusion: This study showed a prevalence of MDR-TB among pulmonary TB patients, which is similar to some of the eastern African countries.Keywords: TB, drug-resistance, poly-drug resistance, MDR, XDR
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