BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE

Nowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its...

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Main Authors: T. A. Pavlenko, O. V. Blagova
Format: Article
Language:Russian
Published: SINAPS LLC 2016-05-01
Series:Архивъ внутренней медицины
Subjects:
Online Access:https://www.medarhive.ru/jour/article/view/521
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author T. A. Pavlenko
O. V. Blagova
author_facet T. A. Pavlenko
O. V. Blagova
author_sort T. A. Pavlenko
collection DOAJ
description Nowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its’ common combinations with another arrhythmias and the presence of Brugada phenocopy. Conjunction of Brugada syndrome with morphological changes in myocardium , especially myocarditis, is an area of special interest. Infl ammation associates with clinical manifestation of the syndrome, and this situation forces to think about channelopathies’ primacy and to look for another possible mechanisms of Brugada syndrome.
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spelling doaj.art-50aed04ecd484910bdbee5769262a7d82023-03-13T07:12:07ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642016-05-0162616910.20514/2226-6704-2016-6-2-61-69512BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATET. A. Pavlenko0O. V. Blagova1Первый Московский государственный медицинский университет им. И.М. СеченоваПервый Московский государственный медицинский университет им. И.М. СеченоваNowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its’ common combinations with another arrhythmias and the presence of Brugada phenocopy. Conjunction of Brugada syndrome with morphological changes in myocardium , especially myocarditis, is an area of special interest. Infl ammation associates with clinical manifestation of the syndrome, and this situation forces to think about channelopathies’ primacy and to look for another possible mechanisms of Brugada syndrome.https://www.medarhive.ru/jour/article/view/521синдром бругадамиокардитканалопатияфенокопияэлектрическое ремоделирование
spellingShingle T. A. Pavlenko
O. V. Blagova
BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
Архивъ внутренней медицины
синдром бругада
миокардит
каналопатия
фенокопия
электрическое ремоделирование
title BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_full BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_fullStr BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_full_unstemmed BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_short BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_sort brugada syndrome from primary electric heart disease to morphological substrate
topic синдром бругада
миокардит
каналопатия
фенокопия
электрическое ремоделирование
url https://www.medarhive.ru/jour/article/view/521
work_keys_str_mv AT tapavlenko brugadasyndromefromprimaryelectricheartdiseasetomorphologicalsubstrate
AT ovblagova brugadasyndromefromprimaryelectricheartdiseasetomorphologicalsubstrate