Ferroptosis in Cardiovascular Disease and Cardiomyopathies: Therapeutic Implications of Glutathione and Iron Chelating Agents

Ferroptosis in Cardiovascular Disease and Cardiomyopathies: Therapeutic Implications of Glutathione and Iron Chelating Agents

This review explores ferroptosis, a form of regulated cell death reliant on iron-induced phospholipid peroxidation, in diverse physiological and pathological contexts, including neurodegenerative disorders, and ischemia-reperfusion. In the realm of cardiovascular diseases, it significantly contribut...

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Bibliographic Details
Main Authors: John Dawi, Scarlet Affa, Edgar Gonzalez, Yura Misakyan, David Nikoghosyan, Karim Hajjar, Samuel Kades, Sabrina Fardeheb, Hayk Mirzoyan, Vishwanath Venketaraman
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Biomedicines
Subjects:
ferroptosis
GPX4
NRF2
GSH
oxidative stress
cardiomyopathy
Online Access:https://www.mdpi.com/2227-9059/12/3/558

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