Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans

Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans

Leishmaniasis is endemic in at least 98 countries. Due to the high toxicity and resistance associated with the drugs, we chose lignans as an alternative, due to their favorable properties of absorption, distribution, metabolism, excretion, and toxicity (ADMET). To investigate their leishmanicidal po...

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Bibliographic Details
Main Authors: Mayara dos Santos Maia, Joanda Paolla Raimundo e Silva, Thaís Amanda de Lima Nunes, Julyanne Maria Saraiva de Sousa, Gabriela Cristina Soares Rodrigues, Alex France Messias Monteiro, Josean Fechine Tavares, Klinger Antonio da Franca Rodrigues, Francisco Jaime B. Mendonça-Junior, Luciana Scotti, Marcus Tullius Scotti
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
leishmaniasis
lignan
virtual screening
molecular docking
computer-aided drug design
Online Access:https://www.mdpi.com/1420-3049/25/10/2281

Internet

https://www.mdpi.com/1420-3049/25/10/2281

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